At The Bench | Cell Culture Lab Techniques and Best Practices from the Nucleus Cell Culture Blog | Corning

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Cell Suspension Culture or Adherent Surface: Which Is Right for Your Lab?

An adherent vessel preserves cell biology, but a cell suspension culture yields scale. But there are other factors, too, like timing and resources.

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Austin Mogen

The Race to Billions: How Amplifying Adherent Cultures Can Get You There

Austin Mogen, Ph.D., senior field application scientist, and Cat Siler, Ph.D., field application scientist, both from Corning Life Sciences, discuss platforms for adherent cell culture scale-up, how to trim time and costs, and how to deliver high-efficiency output across adherent applications.

Austin Mogen, Ph.D., senior...

Austin Mogen, Ph.D., senior field...

Austin Mogen, Ph.D., senior field application scientist, and Cat Siler,...

Austin Mogen, Ph.D., senior field application scientist, and Cat Siler, Ph.D., field application scientist, both...

Austin Mogen, Ph.D., senior field application scientist, and Cat Siler, Ph.D., field application scientist, both from Corning Life Sciences,...

Scientist using serum

Pharma Manufacturing: 6 Questions to Ask When Vetting Serum Suppliers

To ensure that quality serum will be there when needed, here are 6 questions pharma manufacturing labs need to ask serum suppliers before stocking up.

To ensure that quality serum...

To ensure that quality serum will be there...

To ensure that quality serum will be there when needed, here are 6...

To ensure that quality serum will be there when needed, here are 6 questions pharma manufacturing labs need to ask...

To ensure that quality serum will be there when needed, here are 6 questions pharma manufacturing labs need to ask serum suppliers before...

Is a Perfusion Cell Culture System Right for Your Adherent Cultures?

Is a Perfusion Cell Culture System Right for Your Adherent Cultures?

Perfusion cell culture systems help researchers achieve scale with minimal space, variability, and labor. Should you make the switch?

Perfusion cell culture...

Perfusion cell culture systems help...

Perfusion cell culture systems help researchers achieve scale with minimal...

Perfusion cell culture systems help researchers achieve scale with minimal space, variability, and labor. Should...

Perfusion cell culture systems help researchers achieve scale with minimal space, variability, and labor. Should you make the switch?

Suspension or Adherent: Which Method is Right for Your Lab?

Cell Suspension Culture or Adherent Surface: Which Is Right for Your Lab?

An adherent vessel preserves cell biology, but a cell suspension culture yields scale. But there are other factors, too, like timing and resources.

An adherent vessel preserves...

An adherent vessel preserves cell biology,...

An adherent vessel preserves cell biology, but a cell suspension culture...

An adherent vessel preserves cell biology, but a cell suspension culture yields scale. But there are other...

An adherent vessel preserves cell biology, but a cell suspension culture yields scale. But there are other factors, too, like timing and...

Comparing Gene Transfer Tools: Adeno-Associated Virus and Lentiviral Vectors

Comparing Gene Transfer Tools: Adeno-Associated Virus and Lentiviral Vectors

Should you use adeno-associated virus or lentivirus vectors in your lab? Each gene transfer tool has advantages, disadvantages, and scaling considerations.

Should you use...

Should you use adeno-associated virus or...

Should you use adeno-associated virus or lentivirus vectors in your lab?...

Should you use adeno-associated virus or lentivirus vectors in your lab? Each gene transfer tool has advantages,...

Should you use adeno-associated virus or lentivirus vectors in your lab? Each gene transfer tool has advantages, disadvantages, and scaling...

Optimizing Stem Cell Production With Modern-Day Lab Technologies

Optimizing Stem Cell Production With Modern-Day Lab Technologies

Despite excitement around human MSCs, many challenges remain. These lab tools can help scientists overcome them and improve cell production and quality.

Despite excitement around...

Despite excitement around human MSCs, many...

Despite excitement around human MSCs, many challenges remain. These lab...

Despite excitement around human MSCs, many challenges remain. These lab tools can help scientists overcome them...

Despite excitement around human MSCs, many challenges remain. These lab tools can help scientists overcome them and improve cell production and...

Chris Suarez, Ph.D.

How to Select the Right Platform for Your Vaccine Production Process

Researchers have choices when selecting adherent platforms for vaccine production. Consider surface area, desired yield, and labor to find the right one.

Researchers have choices when...

Researchers have choices when selecting...

Researchers have choices when selecting adherent platforms for vaccine...

Researchers have choices when selecting adherent platforms for vaccine production. Consider surface area, desired...

Researchers have choices when selecting adherent platforms for vaccine production. Consider surface area, desired yield, and labor to find the...

X-WASH System

How Closed, Automated Cell Separation Systems Reduce Contamination Risk

Every step in the cell separation process comes with inherent contamination risks. A closed system can help you manage them.

Every step in the cell...

Every step in the cell separation process...

Every step in the cell separation process comes with inherent...

Every step in the cell separation process comes with inherent contamination risks. A closed system can help you...

Every step in the cell separation process comes with inherent contamination risks. A closed system can help you manage them.

Ranya Badran

Selecting the Best Cold Storage Solution for your Lab: Preserve Samples for Experimental Success

Ranya Badran, Corning, discusses the importance of sample preservation over time and reveals state-of-the-art cooling tools that protect precious samples.

Ranya Badran, Corning,...

Ranya Badran, Corning, discusses the...

Ranya Badran, Corning, discusses the importance of sample preservation...

Ranya Badran, Corning, discusses the importance of sample preservation over time and reveals state-of-the-art...

Ranya Badran, Corning, discusses the importance of sample preservation over time and reveals state-of-the-art cooling tools that protect...

Dr. Veronica Gil

Personalized Medicine: Emerging Organoid Models to Better Treat Prostate Cancer

Dr. Veronica Gil discusses how 3D cell culture is enabling scientists to develop and craft organ-specific tissues from stem cells to transform prostate cancer therapy.

Dr. Veronica Gil discusses...

Dr. Veronica Gil discusses how 3D cell...

Dr. Veronica Gil discusses how 3D cell culture is enabling scientists to...

Dr. Veronica Gil discusses how 3D cell culture is enabling scientists to develop and craft organ-specific tissues...

Dr. Veronica Gil discusses how 3D cell culture is enabling scientists to develop and craft organ-specific tissues from stem cells to transform...

HYPERFlask

Looking for an Easier Way to Scale-up Your Benchtop Cell Cultures?

Although the T-175 flasks, and its other sized siblings, are tried-and-true workhorses of the cell culture bench, they offer limited options when you want to scale-up. Which is what makes the Corning High Yielding Performance Flask (HYPERFlask) cell culture vessel such an innovative solution.

Although the T-175 flasks,...

Although the T-175 flasks, and its other...

Although the T-175 flasks, and its other sized siblings, are...

Although the T-175 flasks, and its other sized siblings, are tried-and-true workhorses of the cell culture bench,...

Although the T-175 flasks, and its other sized siblings, are tried-and-true workhorses of the cell culture bench, they offer limited options...

Joseph Regan

The Intersection of Art and Science: Q&A With Dr. Joseph Regan

Q&A with Dr. Joseph Regan, Ph.D., biologist and artist, on his process, his interests, and what he wants scientists to know about the interplays between art, science, and life.

Q&A with Dr. Joseph...

Q&A with Dr. Joseph Regan, Ph.D.,...

Q&A with Dr. Joseph Regan, Ph.D., biologist and artist, on his...

Q&A with Dr. Joseph Regan, Ph.D., biologist and artist, on his process, his interests, and what he wants...

Q&A with Dr. Joseph Regan, Ph.D., biologist and artist, on his process, his interests, and what he wants scientists to know about the...

Scientist working under the hood

Overcoming the Challenges of Scaling Up Adherent Cells

This article highlights some common causes of these adherent cell culture issues and provides helpful suggestions for preventing them, both during routine cell culture and scale up.

This article highlights some...

This article highlights some common causes...

This article highlights some common causes of these adherent cell culture...

This article highlights some common causes of these adherent cell culture issues and provides helpful suggestions...

This article highlights some common causes of these adherent cell culture issues and provides helpful suggestions for preventing them, both...

Innovative, Break-resistant & Leak-proof PET Media Bottles

Innovative, Break-resistant & Leak-proof PET Media Bottles

To meet the growing demand for aqueous solution storage, Corning offers a wide range of its newest PET media bottles which offer an easy to handle and highly ergonomic efficient alternative to glass.

To meet the growing demand...

To meet the growing demand for aqueous...

To meet the growing demand for aqueous solution storage, Corning offers a...

To meet the growing demand for aqueous solution storage, Corning offers a wide range of its newest PET media...

To meet the growing demand for aqueous solution storage, Corning offers a wide range of its newest PET media bottles which offer an easy to...

Scientist working with media bag

5 Things to Consider When Customizing Cell Culture Media (and Other Reagents)

Whether you're making new formulations for cell culture media or fulfilling exact-volume packaging, custom solutions bring benefits to every lab.

Whether you're making new...

Whether you're making new formulations for...

Whether you're making new formulations for cell culture media or...

Whether you're making new formulations for cell culture media or fulfilling exact-volume packaging, custom...

Whether you're making new formulations for cell culture media or fulfilling exact-volume packaging, custom solutions bring benefits to every...

Scientist in Lab

Process Development in Gene Therapy: 4 Things to Know

One small misstep in process development in gene therapy can create huge gaps between outcomes and expectations. Scale up smarter with these 4 tips for gene therapy process development.

One small misstep in process...

One small misstep in process development in...

One small misstep in process development in gene therapy can create huge...

One small misstep in process development in gene therapy can create huge gaps between outcomes and expectations....

One small misstep in process development in gene therapy can create huge gaps between outcomes and expectations. Scale up smarter with these 4...

Vaccine Production

Vaccine Production Process Development: 4 Best Practices for Scaling Up

How can researchers working on vaccine production optimize their process with customization in mind? Corning provides 4 best practices for scaling vaccine production process development.

How can researchers working...

How can researchers working on vaccine...

How can researchers working on vaccine production optimize their process...

How can researchers working on vaccine production optimize their process with customization in mind? Corning...

How can researchers working on vaccine production optimize their process with customization in mind? Corning provides 4 best practices for...

Cancer Cells

Could Halting Cancer Cell Motility Stop Metastasis in Its Tracks?

Cancer spreads because its cells are motile. Interrupting that motility could be the key to stopping cancer cell metastasis.

Cancer spreads because its...

Cancer spreads because its cells are motile....

Cancer spreads because its cells are motile. Interrupting that motility...

Cancer spreads because its cells are motile. Interrupting that motility could be the key to stopping cancer cell...

Cancer spreads because its cells are motile. Interrupting that motility could be the key to stopping cancer cell metastasis.

How to Set Up a New Lab From Scratch

How to Set Up a New Lab From Scratch

Wondering how to set up a new lab from scratch? These tips can help you get going safely, quickly, and effectively.

Wondering how to set up a new...

Wondering how to set up a new lab from...

Wondering how to set up a new lab from scratch? These tips can help you...

Wondering how to set up a new lab from scratch? These tips can help you get going safely, quickly, and...

Wondering how to set up a new lab from scratch? These tips can help you get going safely, quickly, and effectively.

Cost Efficient R&D Scale Up for Insect Cell Recombinant Protein Production

Cost Efficient R&D Scale Up for Insect Cell Recombinant Protein Production

Recently, Dr. Ciaran Cronin and his team at Pfizer La Jolla demonstrated a more cost-efficient method for scaling up recombinant protein production in the baculovirus expression vector system (BEVS) using large Erlenmeyer flasks and standard laboratory equipment.

Recently, Dr. Ciaran Cronin...

Recently, Dr. Ciaran Cronin and his team at...

Recently, Dr. Ciaran Cronin and his team at Pfizer La Jolla demonstrated a...

Recently, Dr. Ciaran Cronin and his team at Pfizer La Jolla demonstrated a more cost-efficient method for scaling...

Recently, Dr. Ciaran Cronin and his team at Pfizer La Jolla demonstrated a more cost-efficient method for scaling up recombinant protein...

The Dos and Don'ts of Cryopreservation

The Dos and Don’ts of Cryopreservation

For this Cell Culture Dish Ask the Expert Session, we have assembled a team of experts to answer your questions on cryopreservation.

For this Cell Culture Dish...

For this Cell Culture Dish Ask the Expert...

For this Cell Culture Dish Ask the Expert Session, we have assembled a...

For this Cell Culture Dish Ask the Expert Session, we have assembled a team of experts to answer your questions on...

For this Cell Culture Dish Ask the Expert Session, we have assembled a team of experts to answer your questions on cryopreservation.

Scientist handling a CoolBox in a freezer

Your Guide to the Cryopreservation of Cells

Cryopreservation of cells puts your cell lines in suspended animation, stopping biological time for your cell cultures.

Cryopreservation of cells...

Cryopreservation of cells puts your cell...

Cryopreservation of cells puts your cell lines in suspended animation,...

Cryopreservation of cells puts your cell lines in suspended animation, stopping biological time for your cell...

Cryopreservation of cells puts your cell lines in suspended animation, stopping biological time for your cell cultures.

Scientist operates Corning® Automated Manipulator Platform

Working With Viral Vectors: New Trends to Optimize Your Workflow

These new trends in viral vector production and cell culture technology can help you overcome them.

These new trends in viral...

These new trends in viral vector production...

These new trends in viral vector production and cell culture technology...

These new trends in viral vector production and cell culture technology can help you overcome them.

These new trends in viral vector production and cell culture technology can help you overcome them.

Scientist working with cell growth equipment

What's Killing My Cell Cultures?: Troubleshooting Cell Growth Issues

Nothing's more maddening than cells that won't grow. This guide can help you find out what's stalling your cell growth — and how to fix it.

Nothing's more maddening than...

Nothing's more maddening than cells that...

Nothing's more maddening than cells that won't grow. This guide can help...

Nothing's more maddening than cells that won't grow. This guide can help you find out what's stalling your cell...

Nothing's more maddening than cells that won't grow. This guide can help you find out what's stalling your cell growth — and how to fix it.

Scientist working with bioprocessing products

Scalable High Yield System for Mass Culture of Attachment-Dependent Cells

Read about CellCube on Cell Culture Dish, including an interview with Dr. Ann Rossi.

Read about CellCube on Cell...

Read about CellCube on Cell Culture Dish,...

Read about CellCube on Cell Culture Dish, including an interview with Dr....

Read about CellCube on Cell Culture Dish, including an interview with Dr. Ann Rossi.

Read about CellCube on Cell Culture Dish, including an interview with Dr. Ann Rossi.

Cell Type Surface Guide: How to Pick the Right Coatings

Cell Type Surface Guide: How to Pick the Right Coatings

By using the optimal cell type surface in your research, you can achieve your desired endpoints. Here's how to pick the right one.

By using the optimal cell...

By using the optimal cell type surface in...

By using the optimal cell type surface in your research, you can achieve...

By using the optimal cell type surface in your research, you can achieve your desired endpoints. Here's how to...

By using the optimal cell type surface in your research, you can achieve your desired endpoints. Here's how to pick the right one.

Scientist working with hyperflask

How to Minimize Contamination Risk and Protect your Cultures

For this Ask the Expert Session, The Cell Culture Dish assembled a team of experts to answer questions on contamination and minimizing risk. 

For this Ask the Expert...

For this Ask the Expert Session, The Cell...

For this Ask the Expert Session, The Cell Culture Dish assembled a team of...

For this Ask the Expert Session, The Cell Culture Dish assembled a team of experts to answer questions on...

For this Ask the Expert Session, The Cell Culture Dish assembled a team of experts to answer questions on contamination and minimizing...

Scientist working under hood with pipettor

Five Easy Ways to Keep Your Cell Cultures Endotoxin-Free

This Biocompare article looks at best practices to reduce the risk of endotoxin contamination.

This Biocompare article looks...

This Biocompare article looks at best...

This Biocompare article looks at best practices to reduce the risk of...

This Biocompare article looks at best practices to reduce the risk of endotoxin contamination.

This Biocompare article looks at best practices to reduce the risk of endotoxin contamination.

Scientist Wearing Protective Equipment

Tips for Lab Safety During a Pandemic

As COVID-19 cases rise, now is the time to protect your laboratory, your lab mates, and yourself by strictly abiding to lab safety rules.

As COVID-19 cases rise, now...

As COVID-19 cases rise, now is the time to...

As COVID-19 cases rise, now is the time to protect your laboratory, your...

As COVID-19 cases rise, now is the time to protect your laboratory, your lab mates, and yourself by strictly...

As COVID-19 cases rise, now is the time to protect your laboratory, your lab mates, and yourself by strictly abiding to lab safety rules.

Scientist working with liquid pipettor and coolbox

Top Tips for Freezing and Thawing Cells to Maintain Viability

This article by Biocompare discusses best practices for freezing and thawing cells to maintain a high viability.

This article by Biocompare...

This article by Biocompare discusses best...

This article by Biocompare discusses best practices for freezing and...

This article by Biocompare discusses best practices for freezing and thawing cells to maintain a high viability.

This article by Biocompare discusses best practices for freezing and thawing cells to maintain a high viability.

cryopreservation

3D Cell Cryopreservation Best Practices

Cryopreservation of cells and cell lines is a key technique in 3D cell culture. 

Cryopreservation of cells and...

Cryopreservation of cells and cell lines is...

Cryopreservation of cells and cell lines is a key technique in 3D cell...

Cryopreservation of cells and cell lines is a key technique in 3D cell culture. 

Cryopreservation of cells and cell lines is a key technique in 3D cell culture. 

3D Organoids

3D Organoids Lead the Way for Personalized Cancer Therapy

The tiny organs made possible by 3D organoids enable scientists to test and optimize cancer therapies better than ever before.

The tiny organs made possible...

The tiny organs made possible by 3D...

The tiny organs made possible by 3D organoids enable scientists to test...

The tiny organs made possible by 3D organoids enable scientists to test and optimize cancer therapies better than...

The tiny organs made possible by 3D organoids enable scientists to test and optimize cancer therapies better than ever before.

Biofabrication

Biofabrication and Cell Therapy: Where We Are (and Where We're Going)

Biofabrication is the next frontier of regenerative medicine, and its applications hold exciting promise in many clinical areas.

Biofabrication is the next...

Biofabrication is the next frontier of...

Biofabrication is the next frontier of regenerative medicine, and its...

Biofabrication is the next frontier of regenerative medicine, and its applications hold exciting promise in many...

Biofabrication is the next frontier of regenerative medicine, and its applications hold exciting promise in many clinical areas.

Cell Culture Containment

Cell Contamination, Containment, and Correction: Good Cell Culture Practices in 3D

Learn about contamination prevention in the lab, what can cause the contamination, and post contaminant procedures.

Learn about contamination...

Learn about contamination prevention in the...

Learn about contamination prevention in the lab, what can cause the...

Learn about contamination prevention in the lab, what can cause the contamination, and post contaminant...

Learn about contamination prevention in the lab, what can cause the contamination, and post contaminant procedures.

Scientists in lab

Lab Best Practices: 10 Ways to Be an MVP in Your Lab

Follow these lab best practices to be the best labmate you can be. Learn proper lab etiquette, proper attire, procedures and more.

Follow these lab best...

Follow these lab best practices to be the...

Follow these lab best practices to be the best labmate you can be. Learn...

Follow these lab best practices to be the best labmate you can be. Learn proper lab etiquette, proper attire,...

Follow these lab best practices to be the best labmate you can be. Learn proper lab etiquette, proper attire, procedures and more.

Organoids & Spheroids

Organoid vs. Spheroid: What's the Difference?

If you're wanting to get started in complex 3D cell culture, you'll need to learn the organoid vs. spheroid difference. 

If you're wanting to get...

If you're wanting to get started in complex...

If you're wanting to get started in complex 3D cell culture, you'll need...

If you're wanting to get started in complex 3D cell culture, you'll need to learn the organoid vs. spheroid...

If you're wanting to get started in complex 3D cell culture, you'll need to learn the organoid vs. spheroid difference. 

Transfection

What Is Transfection?

Learn what transfection is, its connection to 3D cell culture, and the innovate strategies for 3D transfection.

Learn what transfection is,...

Learn what transfection is, its connection...

Learn what transfection is, its connection to 3D cell culture, and the...

Learn what transfection is, its connection to 3D cell culture, and the innovate strategies for 3D transfection.

Learn what transfection is, its connection to 3D cell culture, and the innovate strategies for 3D transfection.

High Throughput Screening

What Is High Throughput Screening and How Is It Evolving?

Learn about high-throughput screening and how it's used as an early-stage tool for drug discovery.

Learn about high-throughput...

Learn about high-throughput screening and...

Learn about high-throughput screening and how it's used as an early-stage...

Learn about high-throughput screening and how it's used as an early-stage tool for drug discovery.

Learn about high-throughput screening and how it's used as an early-stage tool for drug discovery.

Tissue Engineering

Tissue Engineering: The Short- and Long-Term Benefits of Bioprinting

Examine the benefits of 3D bioprinting and bio fabrication, including tissue engineering, replacement printing, disease modeling, complete organ replacement, and organ regeneration.

Examine the benefits of 3D...

Examine the benefits of 3D bioprinting and...

Examine the benefits of 3D bioprinting and bio fabrication, including...

Examine the benefits of 3D bioprinting and bio fabrication, including tissue engineering, replacement printing,...

Examine the benefits of 3D bioprinting and bio fabrication, including tissue engineering, replacement printing, disease modeling, complete organ...

Cancer Research

Cancer Research

Corning experts through The Cell Culture Dish will be answering your questions on cancer research – our scientists are ready to support you in areas ranging from 3D cell culture to tumor formation and angiogenesis to invasion/migration assays

Corning experts through The...

Corning experts through The Cell Culture...

Corning experts through The Cell Culture Dish will be answering your...

Corning experts through The Cell Culture Dish will be answering your questions on cancer research – our scientists...

Corning experts through The Cell Culture Dish will be answering your questions on cancer research – our scientists are ready to support you in...

Everything You Ever Wanted to Ask About Corning® Matrigel® Matrix

Everything You Ever Wanted to Ask About Corning® Matrigel® Matrix

The Cell Culture Dish hosted two Corning Matrigel matrix experts on this Ask the Expert Session to discuss the best tips, tricks, and expert advice on the product.

The Cell Culture Dish hosted...

The Cell Culture Dish hosted two Corning...

The Cell Culture Dish hosted two Corning Matrigel matrix experts on this...

The Cell Culture Dish hosted two Corning Matrigel matrix experts on this Ask the Expert Session to discuss the...

The Cell Culture Dish hosted two Corning Matrigel matrix experts on this Ask the Expert Session to discuss the best tips, tricks, and expert...