Infectious Disease Modeling | Corning

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3D Cell Culture: An Indispensable Technology in the Fight Against Infectious Diseases

3D Cell Culture: An Indispensable Technology in the Fight Against Infectious Diseases

The advancement of 3D cell culture disease modeling has allowed researchers to study viral and cellular science more realistically than ever before. 3D modeling is more predictive of biological systems, making in vitro results more easily translated to human patients. As a result, 3D cell culture models are one of the most indispensable technologies in the fight against infectious diseases.

With the emergence of the recent coronavirus pandemic, this need is greater than ever before. But the impact 3D culture can have doesn’t end there. 3D models better represent the physical and biochemical environments that viruses encounter in vivo. This has led to a wide array of new insights into the infectious action of pathogens, ranging from toxoplasma gondii to mycobacterium tuberculosis.

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Air-Liquid Interface Culture Research

Using Air-Liquid Interface in Your Research

Air-liquid interface (ALI) cell cultures could play a growing role in the lab. Here's what you need to know to get started.

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Blue and yellow organoid

Using Organoids for Disease Modeling

Organoid cell culture has transformed cell-based assays in drug discovery and basic biology by conferring physiologic relevance to in vitro cell-based biological models. Discover how Dr. Hans Clevers from the Hubrecth Organoid Technology (HUB), located in Utrecth, The Netherlands, successfully expanded adult stem cell-derived organoids in genetically stable form and ultimately, was able to generate in vitro models of any epithelial disease from any patient.

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Scientist holding test tube

3D Cell Culture Could Drive the Fight Against Infectious Diseases

3D cell culture models are one of the indispensable technologies leading the fight against infectious diseases, which include the novel coronavirus, COVID-19.

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Organoid

Ramping Up Drug, Vaccine and Infectivity Testing With Airway Organoids

Lung and airway organoids are of interest for both drug and vaccine development and are valuable tools for studying infectivity in human respiratory diseases, particularly for challenging viral diseases like COVID-19.

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Publications

Supporting Publications for Infectious Disease Modeling

Models

Tissue Models

Tissue Models

Tissue Models

Explore Tissue Environments with Solid Synthetic Scaffold Models.

Explore Tissue Environments with Solid Synthetic Scaffold Models.

Spheroid Models

Spheroid Models

Spheroid Models

Learn about Spheroid Model Environments.

Learn about Spheroid Model Environments.

Organoid Models

Organoid Models

Organoid Models

Learn more about Organoid Model Environments.

Learn more about Organoid Model Environments.

Support

Scientific Support—Setting a New Industry Standard