Matrigel Matrix | Trusted Extracellular Matrices | Corning

Overview

Corning Matrigel Matrix

Cells behave better on Corning Matrigel matrix—the original, trusted extracellular matrix (ECM).

Nearly 30 years ago, researchers were looking for a way to grow mouse sarcoma cells. The solution? The development of Corning Matrigel matrix. Matrigel is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in such ECM proteins as laminin (a major component), collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.

Today, Matrigel, a natural ECM-based hydrogel is among the most widely used models for 2D and 3D cell culture in vitro. Corning matrigel hydrogel enables you to:

  • Improve the attachment and differentiation of both normal and transformed anchorage-dependent epithelioid cells, as well as other cell types.
  • Better mimic in vivo environments for 2D and 3D cell culture applications.

To support the ever-growing popularity of Matrigel matrix across many applications, Corning has significantly increased the quantity of Matrigel matrix produced. Availability in 2 weeks or less from date of order placement.

The Secret to Choosing the Right ECM: Question Everything Free Poster Download

Question Everything Poster

Request a free poster for your lab & learn about the unquestionable choice: Corning Matrigel® matrix.

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Choosing an ECM

Corning Matrigel Matrix Products and their Applications

Tips for Using Matrigel Matrix

Top Corning Matrigel Matrix Handling Tips

How to Handle Matrigel Matrix

Learn how to store, thaw, dilute, and coat surfaces with Matrigel Matrix in your 2D and 3D cell culture applications with our easy infographic.

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Tips for Working with Corning Matrigel Matrix Aliquots

Tips for Working with Corning Matrigel Matrix Aliquots

Use this infographic for tips and tricks when working with aliquots of Matrigel matrix in organoid culture.

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FAQ

Corning Matrigel Matrix FAQs

From growth factor concentration to cell recovery and storage, learn how to optimize your cell culture with Corning Matrigel matrix.

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Basics of Corning® Matrigel® Matrix

Basics of Corning® Matrigel® Matrix

This webinar introduces basic information on Corning Matrigel matrix and discuss tips and techniques for handling Corning Matrigel matrix.

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A Life Scientist’s How-To Guide on Corning Matrigel Matrix and Organoids

A Life Scientist’s How-To Guide on Corning Matrigel Matrix and Organoids

This guide details best practices to consider for organoid work, as well as how to use Corning Matrigel matrix and other products to support your organ-specific research.

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Matrigel Matrix Case Studies

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Using Organoids for Personalized Medicine: An Interview with Sylvia Boj from HUB

Hear from Dr. Sylvia Boj, Chief Research Officer at Hubrecht Organoid Technology (HUB), to learn more about how researchers are using Corning Matrigel Matrix to generate organoid models for personalized medicine research in hopes to find the right treatment for each individual patient.

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Dennis Plenker

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Dennis Plenker

Hear more about Dennis Plenker’s work and how they are using Corning® Matrigel® matrix.  

Ping Zhou

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Ping Zhou

Hear more about Ping Zhou’s work and how they are using Corning® Matrigel® matrix.  

Matrigel Matrix Guidelines & Application Notes

Tuning the Elastic Moduli of Corning® Matrigel® and Collagen I 3D Matrices by Varying the Protein Concentration

Tuning the Elastic Moduli of Corning® Matrigel® and Collagen I 3D Matrices by Varying the Protein Concentration

In this paper, we investigated the effect of protein concentration on the elastic moduli of Corning Matrigel® matrix and Collagen I gels using a rotational rheometer.

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In Vivo Implantation

In vivo Implantation

Use Matrigel matrix in angiogenesis and human tumor implantation in mice.

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Maintenance of Human iPS Cells

Maintenance of Human iPS Cells

Matrigel for culturing human iPS cells in a feeder-free environment. 

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Protocol for Corning® Matrigel® Basement Membrane Matrix for 3D Culture In Vitro

Protocol for Corning® Matrigel® Basement Membrane Matrix for 3D Culture In Vitro

Step-by-step protocol for on-top MDCK 3D culture and embedded MDCK 3D culture.

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A Novel Method for Generating Single, Intestinal Organoids for High Throughput Screening

A Novel Method for Generating Single, Intestinal Organoids for High Throughput Screening

Here we demonstrate the formation of gastrointestinal organoids derived from human induced pluripotent stem cells (hiPSC) in Corning® 96-well spheroid microplates in combination with Corning Matrigel® matrix, resulting in a single intestinal organoid in each well.

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Methods for Implantation of Corning Matrigel Matrix into Mice and Tissue Fixation

Methods for Implantation of Corning Matrigel Matrix into Mice and Tissue Fixation

Use Matrigel matrix in angiogenesis and human tumor implantation in mice.

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Maintenance of Human iPS Cells in a Feeder-free Culture System

Maintenance of Human iPS Cells in a Feeder-free Culture System

Corning Matrigel matrix is an effective surface that supports feeder-free expansion and maintenance of undifferentiated human iPS cells.

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Corning Matrigel Matrix

View All Matrigel Application Notes

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How to Buy

Purchasing Options

Order Online

Order Online

Order Online

It’s easy to purchase Matrigel matrix online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

It’s easy to purchase Matrigel matrix online. Order direct with a credit card or use a purchase order if you have an account with Corning.

Distributors

Distributors

Contact your authorized distributor to order Matrigel matrix.

Contact your authorized distributor to order Matrigel matrix.

Customer Service

Customer Service

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

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Matrigel Matrix for Organoids

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