Vaccine Manufacturing and Development | Scalable Vaccine Production from Glass Roller Bottles to Bioreactors | Corning

Corning provides a diverse set of single-use products for all your upstream vaccine development and manufacturing needs: Roller bottles are a tried and true technology that will carry you from process optimization to preliminary scale-up.

When it’s time to ramp up vaccine production for clinical trials, the Corning^® CellSTACK^® is a space-saving solution that also allows for modular lab configurations.

And when your company is ready to transition to commercial manufacturing, microsphere technology, such as Corning’s microcarriers, enables high-density culture of adherent cells in bioreactors.

Corning offers a portfolio of products to meet your short- and long-term vaccine manufacturing needs. Here we show a seed train from roller bottles to microcarriers in stirred tank bioreactors. As scale-up progresses, the vessels increase in space efficiency, reducing the cost and minimizing the labor per titer.