Microcarriers for Cell Culture

Microcarriers: Cell Culture Ready to Use and Optimized for Cell Expansion

Corning Microcarriers are designed to simplify your scale-up processes. The microcarriers are sterile, ready-to-use, and available in closed systems packaging to be used directly with bioreactors. Additionally, the microcarriers are surface treated to enhance cell attachment, maximizing cell yield and viability. To get the most out of your production, try Corning Microcarriers.

Microcarrier Cell Culture Features

Consistency – USP Class VI polystyrene material provides a consistent platform
Performance – Corning Microcarriers are offered with a wide variety of surface treatments
Corning Synthemax^® II coated substrate provides a synthetic surface on the microcarriers for stem cell expansion.
Corning CellBIND^® surface treatment enhances cell attachment for difficult-to-culture cells.
Collagen coating
Highest Sterility Assurance Level (SAL) of 10^-6
Certified non-pyrogenic
Available with Aseptic Transfer Caps and as custom through Closed System Solutions
Compatible for use in Corning Disposable Spinner Flasks

Expanding Cells on Corning® Microcarriers

Speed-up Your Scale-up

Speed-up Your Scale-up

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Sterile Corning beads provide the benefits of traditional microcarriers without swelling, washing, or other preparatory steps.

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Optimize Cell Attachment

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Surface	Properties
Corning CellBIND^®	Incorporates more oxygen into the cell culture surface, rendering it more hydrophilic and increasing cell attachment.
Low Concentration Corning Synthemax^® II	Synthetic surface for stem cell expansion. Recommended for MSCs and IPS/ES applications.
Collagen-coated	Extracellular matrix protein enhanced attachment and performance of some cell types.
Untreated	Can be used if cells are difficult to detach from treated surfaces or if a different coating is required.

Aseptically Transfer

Aseptically Transfer with Ease

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Larger bottles of untreated and select surface-treated Corning beads can be fitted with our transfer caps.

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Expedite Your Optimization

Expedite Your Optimization Process

General Guidelines for Use

General Protocol

General Guidelines for Use

General Protocol

Choosing Serum, Medium, and Agitation Rate

In-house studies demonstrate significant impacts on cell attachment and expansion

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Many parameters can impact cell attachment and expansion on microcarriers including microcarrier surface, pH level, and medium. Changes in agitation rate, sparger choice, sparging rate, and impeller design can also impact cell attachment and subsequent expansion on microcarrier beads. To learn more, download our Application Note.

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Featured Resources

Overcoming Bioprocessing Bottlenecks By Combining Adherent And Suspension Systems

Waisman Biomanufacturing has released the results of an internal study where they demonstrate comparability for a new manufacturing platform combining bioreactors and microcarriers using MSCs.

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The Race to Billions: How Amplifying Adherent Cultures Can Get You There

Field application scientists discuss adherent cell culture scale-up platforms, how to trim time and costs, and how to deliver high-efficiency output.

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Efficient Expansion of Human Mesenchymal Stem Cells on Synthetic Microcarriers in Serum-free, Defined Medium Using Bead-to-Bead Transfer

Read how Corning microcarriers were used to expand bone marrow-derived hMSCs for multiple passages in animal component-free medium by bead-to-bead transfer without the need for enzymatic dissociation.

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Using the Corning HYPERStack® Cell Culture Vessel and Enhanced Attachment Microcarriers for Scale-up and Production in the Vaccine Industry

Enhance viral transduction efficiency by increasing surface area without expanding your spatial footprint using Corning HYPER technology and microcarrier beads.

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Dynamic Expansion of Vero and MRC-5 Cells Using Corning Microcarriers

The surface-area-to-volume ratio and scalability of Corning microcarriers make them an ideal choice for the expansion of Vero and MRC-5 cells. This study shows how these microcarriers enable improved optimization and culturing of adherent cells in dynamic cultures.

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Purchasing Options

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It’s easy to purchase Corning Microcarriers online.

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It’s easy to purchase Corning Microcarriers online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

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Distributors

Contact your authorized Corning distributor.

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Many distributors offer Corning Microcarriers.

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Customer Service

Easy Access to Customer Service and Support

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

Microcarriers for Cell Culture | Corning

Corning® Microcarriers

Microcarriers: Cell Culture Ready to Use and Optimized for Cell Expansion