14th Annual Bioprocessing Summit | Corning

14th Annual Bioprocessing Summit

Corning will showcase its solutions for cell culture scale-up from research to production in booth #306 at the Annual Bioprocessing Summit, August 15 - 18, 2022 in Boston.

Featured solutions will include:


14th Annual Bioprocessing Summit

Schedule of Events

Presentation
August 17
TimeTitleDescriptionPresenterLocation
9:30–10:00 a.m.Expression Cassette Optimization – A Contextually Aware Platform for Expression Vector Optimization and ManufactureTransgene optimization often takes a “one size fits all” approach that uses the same optimization process irrespective of a transgene’s desired expression profile. Rather, factors unique to each vector’s use case should be considered during optimization. We have developed the Expression Cassette Optimization (ECO) platform as an AI-driven optimization tool that considers the gene transfer vector, target tissue, and real-world manufacturing constraints to output optimized sequences tailored to each transgene’s desired expression profile. The ECO pipeline interfaces with our discovery-to-GMP pipeline to enable in-house production of high-titer vector by leveraging fixed bed bioreactor technology from the Corning Ascent platform.

Harrison Brown, Ph.D.


Director of Computational Biology


Expression Therapeutics LLC

Stream #1: Upstream Processing, Bioproduction
Technical Poster Presentation
August 15–18
TitleLocation
Corning® Ascent™ Fixed Bed Reactor (FBR), an Automated, Scalable and Closed System for High Efficiency Cell and Gene Therapy ManufacturingExhibit Hall