Cell contamination is a major concern in 3D cell culture labs as well as with more traditional 2D monolayer cultures. If biological contaminants are undetected, they can significantly affect your resulting data, rendering it inaccurate or useless, or make any products manufactured by the cultures unusable.
How do you devise cell culture protocols that prevent contamination? While contamination can be controlled, it cannot be totally eliminated. So, what do you do when contamination inevitably happens?