Disease Modeling | Disease Development and Progression Models | Corning

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Better understand disease development, progression, and treatment options

Better understand disease development, progression, and treatment options

Disease models support our understanding of how disease develops and progresses, as well as potential treatment approaches. Disease models may be generated using more traditional 2D cultures or using more in vivo-like 3D cell culture models, such as organoids, spheroids, or tissue models to mimic disease in a more physiologically relevant environment.

Corning 3D cell culture solutions give you the power to generate and study more complex models that closely mimic in vivo behaviors in human tissues, tumors, and organs – including the lung, kidney, thyroid, liver, brain, intestine, prostate, and pancreas. Corning 3D cell culture solutions support disease modeling work being done in areas like cancer research, skin models, personalized medicine and infectious diseases.  

Lung organoids generated using Corning Matrigel® Matrix and air-liquid interface (ALI) models generated with Transwell® and Falcon® permeable supports are being used to study a variety of diseases, including infectious diseases like COVID-19. Sophisticated 3D models help you understand how infectivity works, how it attacks the body, and how it spreads from one cell to the next. These advanced disease models move us closer to uncovering the best ways to understand, treat and prevent disease.

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Featured Resources

3D Models and Primary Human Pancreatic Cancer

3D Models and Primary Human Pancreatic Cancer

3D Models and Primary Human Pancreatic Cancer

Discover how 3D models are being explored such as neoplastic pancreatic organoids that better mimic in vivo physiology and are thought to be better predictors for compound profiling.

Discover how 3D models are being explored such as neoplastic pancreatic organoids that better mimic in vivo physiology and are thought to be better predictors for compound profiling.

Matrigel Matrix and Organoid Culture

Matrigel Matrix and Organoid Culture

Matrigel Matrix and Organoid Culture

See how 3D organoids cultured from tumor-patient-derived cells potentially will drive drug discovery towards more in-vivo like models and personalized medicine using Matrigel Matrix.

See how 3D organoids cultured from tumor-patient-derived cells potentially will drive drug discovery towards more in-vivo like models and personalized medicine using Matrigel Matrix.

Elplasia

Corning Ultra-Low Attachment Surface and Breast Cancer Spheroid Formation

Corning Ultra-Low Attachment Surface and Breast Cancer Spheroid Formation

One goal of this study was to examine whether tumor spheroids could be generated and analyzed in a format ideal for High Throughput Screening and whether cells cultured on the Corning Ultra-Low Attachment Surface are more sensitive to drug treatments

One goal of this study was to examine whether tumor spheroids could be generated and analyzed in a format ideal for High Throughput Screening and whether cells cultured on the Corning Ultra-Low Attachment Surface are more sensitive to drug treatments

Support

Scientific Support—Setting a New Industry Standard

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