3D Cell Culture Models | Corning

Create in vivo-like functionality with optimized 3D cell culture models

Whether you’re just getting started in 3D cell culture, looking for proven ways to scale up, or moving to high throughput screening, Corning can help you break through the barriers to creating more in vivo-like environments and predictive models. Quickly and efficiently.

For more than 25 years, Corning has delivered innovations that have advanced the science of 3D cell culture. We pioneered the development of novel tools providing easier access to in vivo-like 3D models, such as Corning Matrigel® matrix and Transwell® permeable supports. And we continue to support you with a diverse and evolving portfolio of innovative 3D cell culture products, like the Corning spheroid microplate, as well as workflow solutions, protocols, and expertise.

Corning is committed to working with you in critical areas like cancer biology, tissue engineering, and regenerative medicine – to help you bring safe, effective drugs and therapies to market in less time with greater certainty.

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3D Cell Culture Models

Tissue Models

Tissue Models

Tissue Models

Explore Tissue Environments with Solid Synthetic Scaffold Models.

Explore Tissue Environments with Solid Synthetic Scaffold Models.

Spheroid Models

Spheroid Models

Spheroid Models

Learn about Spheroid Model Environments.

Learn about Spheroid Model Environments.

Organoid Models

Organoid Models

Organoid Models

Learn more about Organoid Model Environments.

Learn more about Organoid Model Environments.

New Products in 3D Cell Culture

Corning Cell Counter

Organoid Counting Software for the Corning Cell Counter

Engineered to account for complex shapes and sizes, the organoid counting software introduces two versions of the 3D counting algorithm.

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Corning Matribot® Bioprinter

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Corning Matribot® Bioprinter

The first benchtop device to dispense and print Corning Matrigel matrix – and other ECM hydrogels – with ease.

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Matrigel Matrix-3D Plates

Matrigel Matrix-3D Plates

Corning is pleased to offer our Matrigel matrix-3D plates, a pre-coated, ready-to-use option available in 96-well and 384-well formats.

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Elplasia plates

Elplasia® Plates

Elplasia plates generate, culture, and analyze your spheroids all in a standard plate footprint. 

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3D Clear Tissue Clearing Reagent

3D Clear Tissue Clearing Reagent

Clear 3D cell culture models with minimal changes to morphology and without compromising sensitivity.

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Technical Documents

Application Support for 3D Cell Culture

Featured Resources

Matribot

AUTOMATE TO ACCELERATE: Meet the Corning Matribot Bioprinter

Looking to take your lab to the next level with benchtop bioprinting? Learn 7 facts about how the Matribot bioprinter can get you there.

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Matrigel matrix

Corning Matrigel Matrix

Corning Matrigel matrix is being used in cutting edge applications across 3D cell culture, including organoid assays. 

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Cell screening

CAR-T Cell Screening

Discover how you can better mimic the in vivo tumor microenvironment to bridge the gap between successful in vitro studies and success in clinical trials.

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Spheroid microplate

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Video: Don't Let 2D Cell Culture Hold You Back

Hear from Tim Spicer, Director of Discovery Biology and HTS at The Scripps Institute, about how Corning spheroid microplates simplify and streamline the creation of 3D cultures in an HTS environment.

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Assay microplates

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Video: Combining 3D Cell Culture Assays with Live Imaging

Hear from Brad Larson, Principal Scientist at BioTek Instruments, Inc, about how to combine the Cytation 5 with Corning spheroid & high content microplates to easily perform assays & simplify 3D spheroid workflow.

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Organoid

Organoids, Disease Models and 3D Printing: The Challenges and Opportunities for 3D Cell Culture

Learn about the advantages of culturing cells in three dimensions & look at the exciting new developments for the technology behind 3D cell culture.

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3D Cell Culture Ebook

e-Book: 3D Model Systems: Spheroids, Organoids and Tissue Models

Spheroids, organoids & more complex 3D systems have been invaluable to research. Download this guide demystifying 3D models with helpful tips & techniques to set your 3D culture up for success.

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Why HUB Organoids are Key to Advancing Personalized Cancer Therapies

Why HUB Organoids are Key to Advancing Personalized Cancer Therapies

Hubrecht Organoid Technology (HUB) details how patient-derived organoids are becoming promising models for personalized treatment using 3D cell culture technologies from Corning and Yamaha Corporation.

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Organoid

Using Organoids in the Study of Infectious Diseases

Organoid cell culture has transformed cell-based assays in drug discovery and basic biology by conferring physiologic relevance to in vitro cell-based biological models.

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Organoid

e-Book: All about Organoids

Download the "All about Organoids" e-book to learn more about how to efficiently generate organoids, whether its for basic biology, disease modeling, drug discovery, personalized medicine, or regenerative medicine.

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Organoid

e-Book: Expert Guide to Advanced 3D Cell Culture

Download this e-book to learn more about 3D techniques used in basic research, as well as translational and clinical applications. 

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Applications in 3D Cell Culture

Support

Scientific Support – Setting a New Industry Standard

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3D Spheroid-qualified Primary Human Hepatocytes

3D Spheroid-qualified Primary Human Hepatocytes

Enabling 3D liver spheroid models in drug discovery and development.

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Corning® 96- and 384-Well Spheroid Microplates

Corning® 96- and 384-Well Spheroid Microplates

Corning spheroid microplates feature an ultra-low attachment surface. This surface treatment inhibits specific and nonspecific immobilization, which forces cells into a suspended state thus allowing for 3D spheroid formation. 

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Transwell® Permeable Supports

Transwell® Permeable Supports

Create in vivo-like cell culture environment using Transwell permeable supports to enhance cell growth for both anchorage-dependent and feeder-independent cell lines.

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Related Products

You may also be interested in these related products.

Corning 96- and 384-Well Spheroid Microplates

Corning 96- and 384-Well Spheroid Microplates

Corning spheroid microplates feature an ultra-low attachment surface, a unique hydrogel surface designed to prevent cell attachment. This surface treatment inhibits specific and nonspecific immobilization, which forces cells into a suspended state thus allowing for 3D spheroid formation.

Corning spheroid microplates feature an ultra-low attachment surface. This surface treatment inhibits specific and nonspecific immobilization, which forces cells into a suspended state thus allowing for 3D spheroid formation.

3D Spheroid-qualified Primary Human Hepatocytes

3D Spheroid-qualified Primary Human Hepatocytes

Enabling 3D liver spheroid models in drug discovery and development.

Enabling 3D liver spheroid models in drug discovery and development.

Transwell® Permeable Supports

Transwell® Permeable Supports

Create in vivo-like cell culture environment using Transwell permeable supports to enhance cell growth for both anchorage-dependent and feeder-independent cell lines.

Create in vivo-like cell culture environment using Transwell permeable supports to enhance cell growth for both anchorage-dependent and feeder-independent cell lines.