Presenter: Mr. Marc Winter

What are the ideal conditions and hurdles to move to flow chemistry? The benefits of microreactors and flow chemistry have been demonstrated across the chemical manufacturing industry for a variety of processes, but not every process is a good candidate.

Attend this webinar to identify the potential benefits of switching to flow chemistry and gather general advice and hints that will help you decide if flow chemistry would be a good fit for your process.

Session #1
Tuesday, January 12
10:00am Central European Time
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Session #2
Thursday, January 14
11:00am Eastern Standard Time
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Presenter: Dr. Philippe Roth

Due to its interaction with matter, ultraviolet (UV) light can trigger specific reactions and open new routes. Photochemistry is a powerful tool but is often underused by scientists. However, with the improvement of global photochemistry technologies and increased adoption of flow chemistry, new options have emerged. This course highlights the key parameters to look at while performing photochemistry using Advanced-Flow Reactor Technology.

Session #1
Tuesday, January 26
10:00am Central European Time
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Session #2
Thursday, January 28
11:00am Eastern Standard Time
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Presenter: Dr. Ancuta Musina

Corning® Advanced-Flow™ Reactors have been designed to maximize the mixing and the heat transfer. Consistent and pulseless flow is a key parameter for flow chemistry  as any fluctuation in the flow of the chemical can cause the final product to drift out of tolerance. Therefore the selection of appropriate dosing pumps is paramount for a successful continuous-flow process. In the same time, to benefit of the reactor's heat transfer efficiency, the choice of the  heat exchange unit is very important. Join this webinar to learn how to pair material dosing lines (e.g., pumps, flow meters) and temperature controllers (e.g., chillers, heat exchangers) with your continuous flow reactor.

Session #1
Tuesday, February 9
10:00am Central European Time
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Session #2
Thursday, February 11
11:00am Eastern Standard Time
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Guest Presenter: Dr. Jean-Christophe Monbaliu

In this webinar, we will illustrate the rationale behind the development of continuous flow processes relying on molecular oxygen. The use of oxygen for large scale preparative applications is often seen as challenging in organic chemistry both for safety and practical issues. The direct use of molecular oxygen will be illustrated for the preparation of value-added intermediates for pharmaceutical production or other high-end applications. The generation and use of much more reactive oxygenated species, such as singlet oxygen, will be documented as well for preparative chemistry and for the oxidative destruction of chemical warfare agents. Such applications rely on the synergistic combination of light, an organic photosensitizer and ground state molecular oxygen. 

Session #1
Tuesday, February 23
9:00am Central European Time
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Session #2
Thursday, February 25
11:00am Eastern Standard Time
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Presenter: Dr. Philippe Roth

Emerging as a mega-trend and shaping the world in a new and most , nanoparticles are everywhere. The ability to synthesize them remains challenging and require extreme and precise. As flow chemistry is a powerful tool for synthesis, it can offer a different way of thinking and synthesizing nanoparticles. This talk shows through different examples the impact flow chemistry can have on the field.

Session #1
Tuesday, March 9
10:00am Central European Time
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Session #2
Thursday, March 11
11:00am Eastern Standard Time
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Presenter: Mr. Marc Winter

Corning AFR Technology has been designed to help the chemical and pharma industries optimize their processes and speed up their time to market. The great R&D work performed by Corning experts leads to a flow chemistry technology which is not only scalable but enables seamless scale-up.

During this webinar we will go through some of the innovation developed and how this enables customers from around the world to move to production inherently safer and quicker while keeping high quality standards. Through examples and case studies we will discuss how achieving production scale is possible as well as process design optimization.

Session #1
Tuesday, March 23
10:00am Central European Time
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Session #2
Thursday, March 25
11:00am Eastern Standard Time
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Chemistry has been traditionally performed using batch processing techniques, but what is flow chemistry and what advantages could it bring to your processes? Over the last 18 years, Corning has brought to the chemical process industry a powerful process intensification platform: Corning® Advanced-Flow™ Reactors (AFR) and their application technologies, which cover lab-scale flow process development to seamless scale-up of flow processes for commercial production.

This webinar provides a short introduction to Corning AFR Technology and describes the advantages of using flow chemistry compared to more conventional batch chemistry. A description of AFR Technology highlights key aspects such as 100x higher mixing, 1000x better heat transfer and the unique seamless scale-up feature. But the main focus of the webinar is on several cases of applications that have been seamlessly transferred from lab scale directly to industrial production.

The six examples shared during the presentation provide a broad overview of the different reasons to switch to flow chemistry. From the high control required for nanoparticles synthesis, the use of forbidden chemistries such as azide, nitration or oxidation, as well as the need to upgrade old chemistries to increase quality and decrease cost or reduce footprint. The real cases shared by our customers around the world provide great insight into the use of flow chemistry from lab to more than 10,000 metric tons/year production.

Synthesis in Chemistry formal lectures and teaching labs tend to be taught using an historic batch process approach. As many chemists are not taught using a flow chemistry approach, most of this knowledge is acquired in batch process. However,  flow chemistry brings powerful options, and this course aims to help you apply the knowledge you have acquired in Batch Chemistry to get insight into flow chemistry.

The presentation describes the classification of chemical reactions based on kinetics and how flow chemistry is suitable for this. Then common mistakes are described (happening either before , during or after the reaction) to help researchers perform their research and avoid common (and often overlooked) issues. The course also includes guidelines to help you know how to switch a process and which steps to follow.

This presentation also provides tips on how to look through research papers to extract data from batch to flow chemistry. This will help research scientists to grasp which piece of information is useful, which one is overlooked and how to make the most of it. This includes reading through reported reaction time for instance.

Lastly, a real case example of a diazo reaction is described, highlighting the process to get there and how to adapt it. This whole approach can be better grasped by research scientists and used in their own project.