Corning Incorporated (NYSE: GLW) today announced two additions to its 3D cell culture portfolio that provide new solutions to support spheroid and organoid culture models.
Elplasia®, a 3D cell culture microplate, features a microcavity technology that enables high volume spheroid formation, culture, and analysis.
A new Matrigel® matrix for organoid culture is optimized to support organoid growth and differentiation.
These portfolio expansions are designed to meet industry growth and demand trends for technology capable of producing high densities of spheroids, as well as generation of complex organoids for drug discovery, cancer research, and other disease modeling applications.
“Corning’s newest 3D cell culture tools are addressing the growing complexity of 3D research and the need to scale spheroid and organoid production for applications across the industry. This includes drug screening, cancer and tumor biology, stem cell biology, cell therapy research, and 3D tissue engineering,” said Keith Olson, vice president of Business Operations and Technology at Corning Life Sciences. “These tools will allow for uniform and highly reproducible formation of organoids and spheroids at the volumes essential to further research in these critical areas.”
Elplasia plate technology was recently acquired by Corning Life Sciences and has been integrated into Corning’s 3D multicellular spheroid product offering. Corning Elplasia plates feature novel well geometries that promote uniform spheroid formation and are available in two surface coatings – Corning Ultra Low Attachment (ULA) surface on round bottom plates and plasma treated (for self-coating) on square bottom plates.
Matrigel matrix for organoid culture is an optimized extracellular matrix that provides a convenient, ready-to-use solution, verified to support organoid growth and differentiation. Each lot has been qualified to form stable “3D dome” structures and provides the matrix stiffness required to support a successful organoid workflow.
Demand for both organoids and spheroids continues to increase with advances in research and technology in 3D cell culture. With the effectiveness of 3D spheroids in many areas of research, including anti-cancer drug screening and in vitro tumor studies, the need for better methods to produce and replicate spheroids of uniform size in mass quantities has emerged. Similarly, organoids have become increasingly popular in disease modeling and drug discovery, as they resemble the composition and functionality of organs.
To learn more about Corning Life Sciences products, please contact a customer service representative at 1-800-492-1110, toll free in the United States; (+1) 1-978-442-2200 internationally; or visit http://www.corning.com/lifesciences.
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Corning (www.corning.com) is one of the world's leading innovators in materials science, with a more than 165-year track record of life-changing inventions. Corning applies its unparalleled expertise in glass science, ceramic science, and optical physics along with its deep manufacturing and engineering capabilities to develop category-defining products that transform industries and enhance people's lives. Corning succeeds through sustained investment in RD&E, a unique combination of material and process innovation, and deep, trust-based relationships with customers who are global leaders in their industries.
Corning's capabilities are versatile and synergistic, which allows the company to evolve to meet changing market needs, while also helping our customers capture new opportunities in dynamic industries. Today, Corning's markets include optical communications, mobile consumer electronics, display technology, automotive, and life sciences vessels. Corning's industry-leading products include damage-resistant cover glass for mobile devices; precision glass for advanced displays; optical fiber, wireless technologies, and connectivity solutions for state-of-the-art communications networks; trusted products to accelerate drug discovery and delivery; and clean-air technologies for cars and trucks.