Corning® Matrigel® Matrix: Material Properties, Applications and Proper Usage
The extracellular matrix (ECM) is a complex material that serves to stabilize tissues, promote cell attachment, and modulate cell functionality by specifically interacting with cell surface receptors. This material has been shown to play structural, biochemical and mechanical roles in the normal growth and differentiation of various cell types. Corning Matrigel Matrix, an ECM-based material isolated from EHS mouse tumors, is a widely used solubilized basement membrane preparation. Based on its physiological composition and functionality, Matrigel Matrix effectively models the physical interplay between diverse cell types and the ECM microenvironment in-vivo.