Access Recording >
Dr. Andrea Adamo, Zaiput Flow Technologies
Trevor Murray, Zaiput Flow Technologies
Dr. Jean-Christophe Monbaliu, University of Liège
Dr. Guillaume Gauron, Corning Reactor Technologies
Flow chemistry provides a rather broad set of advantages that range from process robustness, ease of scale up, to access otherwise very challenging reaction conditions. Harvesting the full benefits of flow chemistry requires in-line work-up capabilities integrated within the flow process. In this talk, we highlight how in-line continuous and scalable liquid-liquid extraction provided by the Zaiput’s line of separators aids in a full continuous process integration which provides safe operation in a compact foot print. Specifically, the minimal internal volume, lack of head space and inherently safe continuous operation of the separators, provide a valuable tool to process hazardous materials. Further, the scalability of the technology provides a straightforward path to the production of larger quantities of material. Among different examples, we will highlight a recently published case where flow reactions and workups are utilized to manage the reactivity and toxicity of α-chloronitroso derivatives in various conditions.