Microcarriers | Cell Expansion and Yield | Corning

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Ready to Use and Optimized for Cell Expansion

Corning Microcarriers are designed to simplify your scale-up processes. The microcarriers are sterile, ready-to-use, and available in closed systems packaging to be used directly with bioreactors. Additionally, the microcarriers are surface treated to enhance cell attachment, maximizing cell yield and viability. To get the most out of your production, try Corning Microcarriers.

Features
 

  • Consistency – USP Class VI polystyrene material provides a consistent platform
  • Performance – Corning Microcarriers are offered with four surface treatments:
  • Corning Synthemax® II substrate creates a synthetic surface on the microcarriers for stem cell expansion. Use Low Concentration for MSC applications and High Concentration for iPS/ES applications.
  • Corning CellBIND® surface treatment infuses the surface of the microcarriers with oxygen to improve cell attachment
  • Positive charge surface treatment
  • Collagen coating
  • Highest Sterility Assurance Level (SAL) of 10-6
  • Certified nonpyrogenic
  • Available as Closed System Solutions

Simplify Your Workflow

Important Parameters to Consider

Selecting a Surface

Corning offers a complete range of attachment-enhancing surfaces.

Not sure which one is optimal for your cells? Call on Corning Scientific Support for help.

Choosing Serum, Medium, and Agitation Rate

In-house studies demonstrate significant impacts on cell attachment and expansion

Many parameters can impact cell attachment and expansion on microcarriers including microcarrier surface, pH level, and medium. Changes in agitation rate, sparger choice, sparging rate, and impeller design can also impact cell attachment and subsequent expansion on microcarrier beads. To learn more, download our Application Note.

Download

Purchasing Options

APPLICATIONS AND USE

Recent Publications

Efficient Expansion of Human Mesenchymal Stem Cells on Synthetic Microcarriers in Serum-free, Defined Medium Using Bead-to-Bead Transfer

Read how Corning microcarriers were used to expand bone marrow-derived hMSCs for multiple passages in animal component-free medium by bead-to-bead transfer without the need for enzymatic dissociation.

Read More

Using the Corning HYPERStack® Cell Culture Vessel and Enhanced Attachment Microcarriers for Scale-up and Production in the Vaccine Industry

Enhance viral transduction efficiency by increasing surface area without expanding your spatial footprint using Corning HYPER technology and microcarrier beads.

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Dynamic Expansion of Vero and MRC-5 Cells Using Corning Microcarriers

The surface-area-to-volume ratio and scalability of Corning microcarriers make them an ideal choice for the expansion of Vero and MRC-5 cells. This study shows how these microcarriers enable improved optimization and culturing of adherent cells in dynamic cultures.

Read More

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