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Corning® High Yield PERformance (HYPER) Technology

Corning® High Yield PERformance (HYPER) Technology

Corning® High Yield PERformance (HYPER) Technology

Overview

Scale-up with Corning HYPER technology.

The next generation High Yield PERformance (HYPER) technology lets you grow large quantities of adherent cells in a compact space. The technology uses a unique gas permeable film to eliminate the air gap within the vessel. This results in a substantial increase in cell growth surface area compared to traditional vessels.

Vessels with Corning’s HYPER technology are available for research applications (Corning HYPERFlask®) and biopharmaceutical production (Corning HYPERStack®). The benefits include:

  • Higher total cell yields than vessels with similar spatial footprints
  • Similar cell morphology, phenotype, and growth compared to traditional vessels
  • Closed system design ideal for large scale production of cells, vaccines, and protein therapeutics (HYPERStack)

Products

HYPER Platform

HYPERFlask ® Cell Culture Vessel

HYPERFlask ® Cell Culture Vessel

Ideal for research applications, the HYPERFlask delivers a 1720 cm2 growth area in the same space of a 175 cm2 flask, enhancing efficiency without increasing the spatial footprint.

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HYPERStack ® Cell Culture Vessel

HYPERStack ® Cell Culture Vessel

Two innovative Corning products—the CellSTACK® culture chamber and the HYPERFlask—are combined into one, delivering the most efficient, scalable solution for large volume production applications.

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About

HYPER Platform

How to Choose

Contact Us

Our Technical Library includes numerous application notes, manuals, poster presentations, protocols, and technical reports for HYPERFlask and HYPERStack vessels. 

If you have questions, please contact our Scientific Support team from the link below.

Our Technical Library includes numerous application notes, manuals, poster presentations, protocols, and technical reports for HYPERFlask and HYPERStack vessels. 

If you have questions, please contact our Scientific Support team from the link below.

Contact Us
How to Use

Learn More

Download detailed specifications and certificates or reach out for one-on-one support and onsite assistance.

Download detailed specifications and certificates or reach out for one-on-one support and onsite assistance.

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How to Buy

Learn More

Get the specific end-to-end solution you need, with the high yield you demand. Call or email Corning to discover how we can support your cell culture scale-up requirements.

Get the specific end-to-end solution you need, with the high yield you demand. Call or email Corning to discover how we can support your cell culture scale-up requirements.

Learn More

Applications and Use

HYPER Platform in Action

Increased Cell Yields

Increased Cell Yields for Cell-based Assays with HYPERFlask Vessel

Discover how the HYPERFlask vessel increases yields for cell-based assays without affecting cell behavior.

Discover how the HYPERFlask vessel increases yields for cell-based assays without affecting cell behavior.

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Generating Lentiviral Particles

Generating Lentiviral Particles in the Corning HYPERStack Vessel

Using an experimental approach to generate lentivirus in the HYPERStack vessel, Corning Applications Group researchers produced equivalent titers and higher yields compared to those generated using standard rigid stacked vessels.

Using an experimental approach to generate lentivirus in the HYPERStack vessel, Corning Applications Group researchers produced equivalent titers and higher yields compared to those generated using standard rigid stacked vessels.

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Scale-Up and Production

Using HYPERStack and Microcarriers for Scale-Up and Production

The focus of this study was to determine the efficacy of generating adenoviral and lentiviral particles using the unique Corning HYPER technology, as well as evaluating the use of enhanced attachment microcarrier beads on cell lines typically used in the vaccine production.

The focus of this study was to determine the efficacy of generating adenoviral and lentiviral particles using the unique Corning HYPER technology, as well as evaluating the use of enhanced attachment microcarrier beads on cell lines typically used in the vaccine production.

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Simplified Production - Influenza A

Large-scale Production of Influenza A Virus Using HYPERFlask Vessel

See how the HYPERFlask vessel, with 10 times more cell growth area than a standard T-175 flask, increases scale-up efficiency by using a single vessel compared to multiple flasks.

See how the HYPERFlask vessel, with 10 times more cell growth area than a standard T-175 flask, increases scale-up efficiency by using a single vessel compared to multiple flasks.

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How to Buy

Purchasing Options

Order Now

Order Now

It’s easy to purchase Corning HYPER technology products online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

It’s easy to purchase Corning HYPER technology products online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

Distributors

Distributors

Many distributors offer the Corning HYPER technology platform.

Many distributors offer the Corning HYPER technology platform.

Customer Service

Customer Service

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

What’s New

Featured Products, Resources, and More

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Corning Media, Sera, and Reagents

Corning Media, Sera, and Reagents

Ensure consistent, reproducible results with high-performance media, sera, and reagents from Corning.

Ensure consistent, reproducible results with high-performance media, sera, and reagents from Corning.

Falcon® Multi-Flask Vessel

Falcon® Multi-Flask Vessel

With an increased growth surface of 525 cm2 or 875 cm2 , the Falcon Multi-flask is a stackable 3- or 5-layer vessel with the same footprint as a T-175 flask and the same proven tissue culture-treated surface as other Falcon flasks.

With an increased growth surface of 525 cm2 or 875 cm2 , the Falcon Multi-flask is a stackable 3- or 5-layer vessel with the same footprint as a T-175 flask and the same proven tissue culture-treated surface as other Falcon flasks.

Bioprocess Products

Bioprocess Products

See our extensive selection of vessels, media, and surface treatments for scaling-up both anchorage-dependent and suspension cells.

Decrease the risk of contamination, eliminate the time and expense of sourcing and assembly, and improve productivity with a custom Corning closed system.

Connect with Corning

Bioprocess Sales Specialists and Field Applications Scientists are always available to offer technical training and process support. Let us help you reach your research goals.

Bioprocess Sales Specialists and Field Applications Scientists are always available to offer technical training and process support. Let us help you reach your research goals.

Contact Us