Fetal Bovine Serum | FBS Manufacturing and Supply | Corning

Fetal Bovine Serum (FBS) is a time tested, universal supplement used in cell culture. It provides many compounds that have been shown to satisfy specific metabolic requirements for the culture of cells, including hormones, growth factors, cell attachment factors, pH buffer, protease inhibitors, vitamins, minerals, lipids, and a variety of undefined components. Serum also protects against toxic effects associated with pH change, the presence of heavy metal ions, endotoxin, and proteolytic activity.

Corning offers a wide variety of fetal bovine serum (FBS) options to satisfy multiple applications from cell culture research to complete bioprocess production. Our FBS is a perfect complement to our classical and custom cell culture media products. We draw on our fully integrated supply chain, comprehensive product offering, and manufacturing capabilities to help you produce consistent, reliable, and reproducible results. 

Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS, even during times of regional supply constraints – assuring you can continue your critical manufacturing work for the long-term. Corning’s direct relationship with abattoirs ensures that collectors use our tools and training and adhere to strict aseptic techniques for blood collection at government approved facilities. Corning Life Sciences is certified for traceability by the International Serum Industry Association (ISIA) and every lot is tested to confirm origin. You can be confident in the source of material from Corning.

FBS Manufacturing

◗ Corning filters serum using 100% single-use technology. During the production process, serum is triple 0.1 micron filtered, true pooled, and aseptically bottled before undergoing rigorous quality testing. Additionally, our innovative heat inactivation process is performed at the lot level, producing a more consistent product when compared with traditional water bath heat inactivation.

◗ For bioproduction customers, Corning’s validated irradiation protocols allows for the flexibility to provide the right product for each customer’s process. Additionally, if our comprehensive Certificate of Analysis does not capture a specific test required, a customized testing solution is available upon request. Please inquire with your local Corning Account Manager for more information.

◗ ISO 13485 Certified Quality Management System

◗ Manufacturing in a cGMP compliant facility operating under 21 CFR 820, Quality System Regulation for Medical Device Manufacturers

◗ Supply chain is certified for traceability by the International Serum Industry Association (ISIA)

◗ Every lot is country-of-origin verified using chemical fingerprinting by Oritain™

◗ Validated irradiation protocols

◗ Certificates of Suitability (CEP) from the European Directorate for the Quality of Medicines (EDQM) for US origin and Australian origin FBS