Corning® Elplasia® Plates | Microplates | Corning

Enable high density, scaffold-free, self-assembly spheroid formation, culture, and analysis in a standard plate footprint.

Overview

Elplasia Plates

With the effectiveness of 3D spheroids in many areas of research including anti-cancer drug screening and in vitro tumor studies, the need for better methods to produce replicate spheroids of uniform size in mass quantities has emerged.

Corning Elplasia plates address this need by enabling researchers to generate a high density of spheroids in a scaffold-free model using microcavity technology. Use Corning Elplasia plates to generate, culture, and analyze hundreds to thousands of spheroids all in a standard plate footprint. Corning Elplasia plates are available in multiple formats, two well geometry types, and two surface coatings.

Elplasia plates are compatible with many cell types and may be used across many applications including; drug screening, including high throughput screening (HTS), cancer/tumor biology, and 3D tissue engineering.

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About

Features and Benefits

Features
Elplasia Microplates Group

Key Features of Elplasia Plates

Key Features of Elplasia Plates

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  • Two well geometry and surface coating options: round bottom type featuring Ultra-Low Attachment (ULA) surface and square bottom type featuring a plasma-treated surface for self-coating
  • Multiple format options: 6-, 24-, 96-. and 384-well
  • Black opaque sidewalls that reduce well-to-well “cross-talk”
  • Plates feature a surface with optical qualities suited for image analysis
  • Gamma irradiated
  • One-year shelf life
  • Two well geometry and surface coating options: round bottom type featuring Ultra-Low Attachment (ULA) surface and square bottom type featuring a plasma-treated surface for self-coating
  • Multiple format options: 6-, 24-, 96-. and 384-well
  • Black opaque sidewalls that reduce well-to-well “cross-talk”
  • Plates feature a surface with optical qualities suited for image analysis
  • Gamma irradiated
  • One-year shelf life
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Benefits
Elplasia workflow

Key Benefits of Elplasia Plates

Key Benefits of Elplasia Plates

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  • Create uniform spheroid formation at large volumes with a simple and easy to use “plug and play” protocol
  • No rinsing required prior to seeding
  • Generate and culture spheroids in one plate – for up to 21 or more days
  • Highly reproducible bulk spheroid formation across microcavity wells – from 79 to 15,000+ spheroids per well
  • Culture a high density of spheroids in one plate under one culture condition
  • Increased signal per well without an increase in spheroid size
  • High density format also generates increased data points, enabling image analysis of multiple spheroids vs. one spheroid per well
  • Suitable for fluorescent/luminescent assays
  • The square well plates are ideal for clonal selection and high magnification imaging of very small clusters
  • Easy for media or buffer change
  • Create uniform spheroid formation at large volumes with a simple and easy to use “plug and play” protocol
  • No rinsing required prior to seeding
  • Generate and culture spheroids in one plate – for up to 21 or more days
  • Highly reproducible bulk spheroid formation across microcavity wells – from 79 to 15,000+ spheroids per well
  • Culture a high density of spheroids in one plate under one culture condition
  • Increased signal per well without an increase in spheroid size
  • High density format also generates increased data points, enabling image analysis of multiple spheroids vs. one spheroid per well
  • Suitable for fluorescent/luminescent assays
  • The square well plates are ideal for clonal selection and high magnification imaging of very small clusters
  • Easy for media or buffer change
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Products

Corning Elplasia Plate Formats

Round Bottom Plates

Corning Elplasia round bottom plates are optimal for bulk spheroid formation, collection, and expansion. Round bottom plates are available in 6-, 24-, and 96-well formats and all feature Corning Ultra-Low Attachment (ULA) surface. Corning ULA surface is proprietary, animal-free, covalently bonded hydrogel surface that is hydrophilic and neutrally charged. The ULA surface promotes the formation and easy harvesting of anchorage-dependent scaffold-free spheroids.

Corning Elplasia round bottom plates are optimal for bulk spheroid formation, collection, and expansion. Round bottom plates are available in 6-, 24-, and 96-well formats and all feature Corning Ultra-Low Attachment (ULA) surface. Corning ULA surface is proprietary, animal-free, covalently bonded hydrogel surface that is hydrophilic and neutrally charged. The ULA surface promotes the formation and easy harvesting of anchorage-dependent scaffold-free spheroids.

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Round Bottom Plate Specs

 

Cat. No.

Description

Number of Spheroids/Well (AVG)

Microwell Size (Diameter/Depth)

Qty/Pk

Qty/Cs

4440

 

Corning Elplasia 6-well round bottom plate, Ultra-Low Attachment (ULA) surface

2885

500/400

1

5

4441

 

Corning Elplasia 24-well round bottom plate, ULA surface

554

500/400

1

5

4442

Corning Elplasia 96-well round bottom microplate, ULA surface

 

79

500/400

1

5

 

Square Bottom Plates

Corning Elplasia square bottom type plates feature a surface with optical qualities suited for image analysis, making them an ideal solution for clonal selection and high magnification imaging of very small clusters. Square bottom plates are plasma-treated for self-coating and come in 6-, 24-, 96-, and 384-well formats.

Corning Elplasia square bottom type plates feature a surface with optical qualities suited for image analysis, making them an ideal solution for clonal selection and high magnification imaging of very small clusters. Square bottom plates are plasma-treated for self-coating and come in 6-, 24-, 96-, and 384-well formats.

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Square Bottom Plate Specs

 

Cat. No.

Description

Number of Spheroids/Well (AVG)

Microwell Size (Diameter/Depth)

Qty/Pk

Qty/Cs

4444

 

Corning Elplasia 6-well square bottom type adherent plate 

15796

200/100

1

5

4445

Corning Elplasia 24-well square type adherent plate

 

2934

200/100

1

5

4446

 

Corning Elplasia 96-well square type adherent microplate

475

200/100

1

5

4447

 

Corning Elplasia 384-well square type adherent microplate

137

200/100

1

5

Applications

Corning Elplasia Plates in Action

Featured Resources

Resources

Green spheroid

Guidelines for Use

Discover how to generate multiple, uniform spheroids in each well of your Corning Elplasia round bottom plates.

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Elplasia Close Image

Corning Elplasia FAQs

From number of spheroids generated to which plate to use, review frequently asked questions about Corning Elplasia plates.

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Spheroid image

HTS of Multiple High Density Scaffold-free Spheroids for Cancer Tox Studies

Learn more about high-throughput screening of 3D cell cultures with multiple high density scaffold-free spheroids for cancer toxicity studies.  

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How to Buy

Purchasing Options

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It’s easy to purchase Corning Elplasia Plates online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

It’s easy to purchase Corning Elplasia Plates online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

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Distributors
Distributors
Customer Service
Customer Service

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If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

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