Osteo Assay | Osteo Assay Surface | Corning

Osteo Assay Surface

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Mimic native bone with the Corning® osteo assay surface and create a more life-like

Mimic native bone with the Corning®

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Reduce assay variability and improve predictability with Corning osteo assay surface, a ready-to-use synthetic surface made of an inorganic crystalline calcium phosphate coating that mimics living bone material. Use the osteo assay surface to enhance bone cell differentiation, functional analysis, and tartrate acide phosphate (TRAP) activity research, along with many other drug discovery applications.

Reduce assay variability and improve predictability with Corning osteo assay surface, a ready-to-use synthetic surface made of an inorganic crystalline calcium phosphate coating that mimics living bone material. Use the osteo assay surface to enhance bone cell differentiation, functional analysis, and tartrate acide phosphate (TRAP) activity research, along with many other drug discovery applications.

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Osteo Assay Surface

About

Osteo Assay Surface

Application

Enables the direct assessment of osteoclast and osteoblast functionality, including bone remodeling and pit formation

Surface Technology

Ready-to-use, sterile, synthetic surface, calcium phosphate micro-crystalline scaffold

Formats

Plates: 24-well and 96-well Corning StripwellTM microplates

Cells

Primary Cells

 

Cell Lines (Transformed or Transfected)

Bone marrow cells

 

RAW 264.7 (macrophage; osteoclast differentiation, pit formation)

 

Human osteoclast precursors (osteoclast, pit formation)

 

 

Peripheral blood mononuclear cells

 

 
TRAP Data
  

Percent TRAP activity of co-cultures expressed as compared to control wells containing RAW 264.7 cells in the presence of RANKL (n=3).

 

 

Soluble TRAP activity found in the medium human osteoclast precursor cells cultured for 5 days on the osteo assay surface.

 

TRAP staining of differentiated human osteoclast precursor cells.

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RAW Data

Visualization of resorption pits from human osteoclast precursor cells and (B) mouse RAW 264.7 resorption pits.

RAW264.7 cells were grown for 7 days in the presence of RANKL on osteo assay surface.

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Applications and Use

Osteo Assay in Action

How to Buy

Purchasing Options

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Browse our online catalog for the latest product information.

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Distributors
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Contact your authorized distributor to order the osteo assay surface.

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Customer Service

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If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

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