Over the last decade, there’s been a rapid emergence of cell and gene therapies in the clinic, transforming patient outlooks for multiple hard-to-treat diseases. One of the main challenges in commercializing cell and gene therapy candidates is translating successful small-scale production techniques into large-scale, cost-effective manufacturing processes that maintain product integrity and prevent contamination.
Closed systems — designed to protect cells during process steps and reduce opportunities for contamination — can increase flexibility, reduce cost, and simplify set up in cell and gene therapy manufacturing.
This whitepaper explores:
- Advantages of closed systems
- Considerations when choosing and setting up closed systems for bioproduction
- Innovative closed system solutions designed for bioproduction labs including:
- Corning® CellSTACK® and HYPERStack® vessels
- Corning CellCube® modules
- Customized configurable assemblies
