Bioprocess Applications | Corning Bioprocessing Applications | Corning

Bridge the Gap Between R&D and Production

Bridge the Gap Between R&D and Production

From research and development to manufacturing, Corning is proud to offer the latest innovative technology to support your advanced therapy applications. From vaccine production to advanced therapy applications, Corning can supply the tools to get you there.

Our cell expansion platforms, from the new Ascent™ Fixed Bed Reactor (FBR) System to the trusted HYPER® and CellSTACK® technologies, are proven to increase efficiency in scale-up, while continuing to deliver reliability and reproducibility, resulting in increased cell viability and yield.  Several of our platforms feature closed systems or automation—thereby reducing risk of contamination, variability, and human error.

Working with these tools supports efficient, successful scale-up, while reducing cost and speeding up time to market, providing a path for your research to translate from the lab to life changing treatments and therapies. Look to Corning’s years of experience in cell culture innovation and our team of field service experts to guide you along your journey to discovery.

From Bench to Billions: Facilitating Scale-Up of Adherent Cultures for Cell and Gene Therapies

Applications

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Vaccine Manufacturing

Vaccine Manufacturing

Vaccine Manufacturing

From HYPERStack and CellSTACK culture chambers to microcarriers and the new Ascent FBR System, Corning provides the full range of tools you'll need to successfully perform and improve adherent-based cultures for vaccine scale-up and production.

From HYPERStack and CellSTACK culture chambers to microcarriers and the new Ascent FBR System, Corning provides the full range of tools you'll need to successfully perform and improve adherent-based cultures for vaccine scale-up and production.

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Immune Cell Therapy

Immune Cell Therapy

Immune Cell Therapy

Look to Corning for clinical cell expansion platforms that can help you scale from research to commercial production. Corning understands your need for clinical cell expansion platforms that scale from research to commercial production to assist in your immune cell therapy research.

Look to Corning for clinical cell expansion platforms that can help you scale from research to commercial production. Corning understands your need for clinical cell expansion platforms that scale from research to commercial production to assist in your immune cell therapy research.

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Gene Therapy

Gene Therapy

Gene Therapy

Corning is working to address the recent surge of interest in gene therapy and the increase in the use of modular manufacturing set-ups for viral vector production, allowing researchers to respond to ever-evolving production needs and enabling a smooth transition from process development to manufacturing.

Corning is working to address the recent surge of interest in gene therapy and the increase in the use of modular manufacturing set-ups for viral vector production, allowing researchers to respond to ever-evolving production needs and enabling a smooth transition from process development to manufacturing.

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Stem Cell Therapy

Stem Cell Therapy

Stem Cell Therapy

Corning offers a wide range of platforms and surface technologies to help drive your stem cell therapy research forward.

Corning offers a wide range of platforms and surface technologies to help drive your stem cell therapy research forward.

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Extracellular Vesicles

Extracellular Vesicles

Extracellular Vesicles

Corning offers a line of products designed for large-scale of stem cell-derived extracellular vesicles (EVs) to impact regenerative medicine and the treatment of inflammatory conditions.

Corning offers a line of products designed for large-scale of stem cell-derived extracellular vesicles (EVs) to impact regenerative medicine and the treatment of inflammatory conditions.

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Cell Production

Cell Production

Cell Production

Corning’s cell culture solutions support your cell production goals, orchestrate discoveries in your lab and scale-up cell expansion to mass production.

Corning’s cell culture solutions support your cell production goals, orchestrate discoveries in your lab and scale-up cell expansion to mass production.

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Seed Train

Seed Train

Seed Train

Whether utilizing suspension or adherent cell culture, an optimized seed train strategy is critical to a successful scale-up.

Whether utilizing suspension or adherent cell culture, an optimized seed train strategy is critical to a successful scale-up.

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Expansion and Processing

Expansion and Processing

Expansion and Processing

Choosing the right cell culture platform is key to meeting production goals.

Choosing the right cell culture platform is key to meeting production goals.

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Harvest and Cryopreservation

Harvest and Cryopreservation

Harvest and Cryopreservation

Closed system solutions can help reduce contamination risk and keep cells viable.

Closed system solutions can help reduce contamination risk and keep cells viable.

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Bioprocessing Products

End-to-End Bioprocess Solutions for Bioproduction Scaling-up

Blog Series

Best Practices for Vaccine Production

Best Practices for Vaccine Production

Best Practices for Vaccine Production

Discover four best practices for scaling up vaccine production process development from an expert in the field.

Discover four best practices for scaling up vaccine production process development from an expert in the field.

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Automated Manipulator

Optimize Your Viral Vector Workflow

Optimize Your Viral Vector Workflow

Learn about the latest trends in viral vector production to help enhance vaccine research development.

Learn about the latest trends in viral vector production to help enhance vaccine research development.

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Chris Suarez, Ph.D.

Vaccine Production: Which Platform Is Best?

Vaccine Production: Which Platform Is Best?

Making the right choice requires scientists to consider a range of factors, from surface area to scale.

Making the right choice requires scientists to consider a range of factors, from surface area to scale.

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Dyno Therapeutics Scaling Up AAV Production using Ascent Fixed Bed Bioreactor System

Dyno Therapeutics Scaling Up AAV Production using Ascent Fixed Bed Bioreactor System

Dyno Therapeutics Scaling Up AAV Production using Ascent Fixed Bed Bioreactor System

Learn how Corning scale-up solutions are assisting our customers with their gene therapy development.

Learn how Corning scale-up solutions are assisting our customers with their gene therapy development.

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Adeno-Associated Virus and Lentiviral Vectors

Adeno-Associated Virus and Lentiviral Vectors

Adeno-Associated Virus and Lentiviral Vectors

AAV and LV vectors can be appealing alternatives to adenoviruses for researchers engaged in viral vector work. Let’s compare the two.

AAV and LV vectors can be appealing alternatives to adenoviruses for researchers engaged in viral vector work. Let’s compare the two.

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Comparing Suspension and Adherent Cell Culture

Comparing Suspension and Adherent Cell Culture

Comparing Suspension and Adherent Cell Culture

Vessel choice is influenced by a myriad of operational and biological factors, such as scale, resources, timing, cell type, and how much — or how little — culture inspection and parameter control is required.

Vessel choice is influenced by a myriad of operational and biological factors, such as scale, resources, timing, cell type, and how much — or how little — culture inspection and parameter control is required.

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Customizing Cell Culture Media

Customizing Cell Culture Media

Customizing Cell Culture Media

There are five important things to consider when determining how to customize your cell culture media or reagent.

There are five important things to consider when determining how to customize your cell culture media or reagent.

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Featured Resources

Guide to Extracellular Vesicles

Guide to Extracellular Vesicles

With more efficient and consistent production methods, researchers will be able to harness the enormous potential of EVs for clinical diagnostics, prognostics, and therapeutics.

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Cell Therapy Ebook

Cell Therapy Ebook: A Comprehensive Look at Key Elements of Cell Production Success

From research scale to clinical and commercial manufacturing, this free downloadable resource offers key considerations and technological expertise for cell therapy production and therapeutic candidate development.

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Achieving High Yield, Versatility, and Scalability for Adherent Cell Culture with Circulation/Perfusion Systems

Achieving High Yield, Versatility, and Scalability for Adherent Cell Culture with Circulation/Perfusion Systems

Learn about circulation/perfusion adherent cell culture platforms and how Corning CellCube offers cost-effective, high-yield cell production.

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Tales, Tips & Teachable Moments from Applications Support Veterans

Tales, Tips & Teachable Moments from Applications Support Veterans

Field application scientists share their experience and expertise from decades of supporting cell culture scientists in academic, biotech and pharma settings

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Viral Vector Manufacturing and Cell Harvesting from a Single Bioreactor?

Viral Vector Manufacturing and Cell Harvesting from a Single Bioreactor?

Corning experts recommend the Ascent Fixed Bed Bioreactor as a solution for adherent cell harvesting and cell product capture.

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HYPERStack Vessels

Increase the Yield of Bone Marrow-derived hMSCs using HYPERStack

See how researchers were able to successfully yield over 870 million human bone marrow-derived MSCs can be obtained from a single HYPERStack 36-layer cell culture vessel.

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Scaling up with HYPER Technology eBook

Ebook: Scaling up with HYPER Technology

Download this guide to improving your scale-up efficiency with HYPER technology from Corning.

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Adherent vs. Suspension

Adherent vs. Suspension Advantages & Disadvantages

Use this infographic to explore which cell culture platform is right for your lab.

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Stack Facts

STACK FACTS: Scaling Up from Research to Clinical Applications

Use this guide to help you choose your ideal Corning vessel for scaling up. Whatever your work requires, Corning’s got you covered.

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Bioprocess Webinars

Support

Field Applications Support

Build a Scale-up Strategy
Field Applications Support: We’re with You Every Step of the Way

We’re With You Every Step of the Way

We’re With You Every Step of the Way

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In the complex world of cell and gene therapy, having a seasoned partner to guide you through uncharted production territory is critical to success.
 
Corning’s Field Applications Scientists have a deep understanding of how the cell culture environment can impact overall cell health, expansion and activity, and how to tailor a culture to suit specific needs. We work with scientists like you to overcome complex manufacturing challenges and streamline the path to production.
In the complex world of cell and gene therapy, having a seasoned partner to guide you through uncharted production territory is critical to success.
 
Corning’s Field Applications Scientists have a deep understanding of how the cell culture environment can impact overall cell health, expansion and activity, and how to tailor a culture to suit specific needs. We work with scientists like you to overcome complex manufacturing challenges and streamline the path to production.
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Quality
Quality that Supports the Path from Research to Production

Quality that Supports the Path from Research to Production

Quality that Supports the Path from Research to Production

With more than 100 years of experience in life sciences, Corning deeply understands the importance of quality. We offer:

  • A proven quality management system
  • Certificates and regulatory documentation
  • BSE/TSE and Sterility

 

Our tried and true manufacturing processes and practices are designed to ensure that every product delivers consistent, reliable results.

With more than 100 years of experience in life sciences, Corning deeply understands the importance of quality. We offer:

  • A proven quality management system
  • Certificates and regulatory documentation
  • BSE/TSE and Sterility

 

Our tried and true manufacturing processes and practices are designed to ensure that every product delivers consistent, reliable results.

Connect with Corning

Connect with Corning

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