3D Spheroid Models | 3D Cell Culture Models | Corning

Spheroids are simple, widely used multicellular 3D models that form due to the tendency of adherent cells to aggregate. They can be generated from a broad range of cell types including tumor spheroids, embryoid bodies, hepatospheres, neurospheres, and mammospheres.

3D multicellular spheroids can develop metabolic gradients that create heterogeneous cell populations with superior cell-to-cell and cell-to-ECM interactions.¹ They offer a more physiologically relevant model as compared to 2D cell culture and can successfully mimic the microenvironment of a variety of tissue types in disease states.

The generation of 3D tumor spheroids in vitro is a useful model to examine malignant cells and tumorigenesis. Discover how to generate functional tumor spheroids using Ultra-Low Attachment surface

Learn more about a 3D model that better mimics the in vivo tumor microenvironment for various chemotherapeutic screens.

Learn how to take the guesswork out of 3D cell culture in HTS environments.

Multicellular tumor spheroids are quickly becoming a valuable tool for studying the tumor microenvironment.

Spheroids, organoids and more complex 3D systems have been invaluable to research. Download this practical guide demystifying 3D models with helpful tips and techniques to set your 3D culture up for success.

Disease models support our understanding of how diseases develop, progress, and treatment options.