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Explore Neural Organoids

Neural organoids—also known as cerebral organoids—are generated from pluripotent stem cells (PSCs). Embryoid bodies derived from induced PSCs (iPSCs) are encapsulated in Corning® Matrigel® Matrix droplets and cultured in differentiation media toward a cerebral phenotype on an agitation-based platform.  These “mini-brains” can help us understand development of the human brain and help evaluate inherited and acquired brain diseases.

Publications

Supporting Publications for Neural Organoids

Supporting Publications for Neural Organoids

Cerebral Organoids and Human Brain Development

Lancaster et al pioneered generation of neural organoids from human PSCs (hPSCs).

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Brain-Region Organoids and ZIKV Exposure

Discover how researchers developed a miniaturized spinning bioreactor (SpinΩ) to generate forebrain-specific organoids from human iPSCs.

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Brain Development and Disease

Recent advances in stem cell technologies that enable the generation of human brain organoids from PSCs may enhance our understanding of the development of the human brain.

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Prospects in Brain Organoid Research

Using a culture system as a model to study human intestinal development, researchers were able to develop human enteroendocrine cells in vitro.

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MLOs and Brain Research

See how researchers successfully cultured midbrain-like organoids (MLOs) bearing features of the human midbrain, which may provide a tractable in vitro system to study the human midbrain and its related diseases.

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