Primary Hepatocytes

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One Proven Brand, from Metabolism Studies Through Pre-clinical Drug Development

Enhance the results of your research with Corning® Gentest™ Hepatic cell models. Corning provides both fresh and cryopreserved primany human hepatocytes to support major applications in drug and xenobiotic biotransformation. Cyropreserved hepatocytes from common pre-clinical animal species are also available. All primary hepatocyte products are pre-screened and extensively characterized, which provides researchers with the data necessary to select lots which are well-suited to their research needs.

To maximize post-thaw viability and recovery of Corning cyropreserved hepatocytes, a cryohepatocyte recovery kit was developed (Cat. No. 454534). The Kit is easy to use and requires only one centrifugation step prior to plating.

Also available now, are the noval Corning HepatoCells. This renewable hepatic cell model is the best alternative to primary human hepatocytes for ADME/Tox studies. 

Corning Gentest Human and Animal Hepatocytes

How to Buy

Purchasing Options

Order Now

Order Now

It’s easy to purchase Corning Gentest hepatocytes online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

It’s easy to purchase Corning Gentest hepatocytes online. Just browse our online catalog, and add products directly to your cart. Order direct with a credit card or use a purchase order if you have an account with Corning.

Distributors

Distributors

Only select distributors in Canada sell Corning Gentest hepatocytes. For global customers outside of Canada, please contact your regional Corning office.

Only select distributors in Canada sell Corning Gentest hepatocytes. For global customers outside of Canada, please contact your regional Corning office.

Customer Service

Customer Service

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

If you need assistance selecting products, or if you’d like to order by phone, fax, or email, please contact us.

How to Buy

Purchasing Options

Applications and Use

Hepatocytes in Action

What’s New

Featured Products, Resources, and Support

Assessing DDI Using Calibration Curve-based Approaches

Assessing DDI Using Calibration Curve-based Approaches

Use of calibration curve methodology and human hepatocytes to predict CYP induction potential.

Assessing DDI Using Calibration Curve-based Approaches with Human Hepatocytes

In a study conducted by Zhang et al., researchers were able to use Corning Gentest human cryohepatocytes to assess the amount of P450 induction in the liver by analyzing the concentration response curves of CYP3A4 mRNA in vitro, and established a predictive relationship between the change in AUC in humans and parameters from CYP3A4 mRNA activity in vivo.

Learn More

Need to Outsource Your Hepatocyte Studies?

Need to Outsource Your Hepatocyte Studies?

Utilize Corning Expertise to get the results you need. Find out what we offer.

Corning Gentest Contract Research Services

With more than 20 years’ experience in supporting drug discovery and development programs, our portfolio of in vitro studies can help address your DDI study needs and more. Corning Gentest Study Directors are knowledgeable and stay up-to-date with rapidly changing technological and regulatory developments.

Read More

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