Corning® PureCoat™ rLaminin Cultureware | Corning Life Sciences

When you’re ready to scale up, you don’t want anything to slow you down. Corning’s family of animal-free, pre-coated cultureware is ready when you are. Corning® PureCoat™ rLaminin-521 cultureware can take you from processing pluripotent and neural stem cells in the lab to full-scale cGMP production – faster than you ever thought possible. 

Corning has collaborated with BioLamina to bring together their expertise in rLaminin-521 expression with Corning’s proprietary surface coating technology that stabilizes the protein for long term stability and functionality. This collaboration brings a robust and scalable expansion solution to the emerging stem cell processing market.

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Experience Simple and Efficient Scale Up

The PureCoat rLaminin-521 cultureware line ensures predictable stem cell culture scale up.

In addition to the handling benefits, PureCoat rLaminin-521 enables ROCK-inhibitor independent single cell passaging. Single cell passaging improves culture consistency and lowers contamination risk compared to labor-intensive clump/colony passaging methods.

Save on the cost of self-coating

When scaling a process under good manufacturing practices, self-coating protocols add validation, labor and facility costs. PureCoat rLaminin-521 provides a 39% cost saving vs. self-coating protocols through the reduction of raw material qualification and protocol validation costs, scrap from incorrect coating, and clean room usage for intermediate coating steps. In addition to these cost savings, PureCoat rLaminin-521 cultureware reduces sterility and variability risk, resulting in a much more efficient and robust cell expansion process.   

Corning PureCoat rLaminin-521 cultureware are animal-free, US Class I medical devices that are manufactured under cGMP in an ISO 13485 certified and FDA registered facility. The animal-free nature of the cultureware mitigates variability and risk of contamination from adventitious organisms common to animal-sourced material.

The surface has long term stability at 2°C to 8°C storage conditions, a 20 month shelf life and can be shipped at ambient temperatures to ease supply chain requirements. PureCoat rLaminin-521 cultureware carries a Sterility Assurance Level (SAL) of 10^-3.