PureCoat ECM Mimetic

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About

Support your clinical research with the scientifically defined, natural performance of Corning PureCoat ECM mimetic cultureware.

Enhance cell culture performance with our next-generation family of chemically defined, animal-free PureCoat surfaces. A proprietary thin-film coating technology produces a uniform, functionalized surface that provides a highly controlled environment for cell culture applications, improving the culturing of animal-free, defined cells without compromising performance.

Choice: Create a fully defined cell culture environment—serum-, xeno-, or animal-free.

Support the growth of stem and primary cells across a broad range of defined media formulations with the choice of two ECM mimetic types:

  • PureCoat ECM mimetic fibronectin peptide consists of RGD sequences to support the attachment of cell types that require fibronectic coating, such as alpha-5 integrin-positive cells. This fibronectic peptide is a compatible, animal-free alternative to natural animal or human ECM surfaces, such as natural human fibronectin for hMSC expansion and differentiation.
  • PureCoat ECM mimetic collagen I peptide supports the attachment of collagen I-dependent cell types, including alpha 2 integrin-positive cells, among others. It provides a compatible, animal-free alternative to natural animal or human ECM surfaces, such as natural human collagen I for human keratinocytes expansion.
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Cells

Features

• Animal component-free, synthetic peptide coating covalently attached to cultureware
• Manufactured in compliance with cGMP and certified to ISO 9001 and ISO 13485
• Compatible with a wide range of serum-free, xeno-free, and animal-free media formulations
• Sterile, SAL10-3, and nonpyrogenic
• Non-cytotoxic
• Quality control tested using an appropriate cell attachment assay
• Room temperature stable 18 months from date of manufacture
• Raw materials tested and meets USP Class VI requirements
• Compatible with a broad range of cell dissociation reagents
• Lot traceable; certificate of compliance available upon request

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Benefits

  • Enables a fully defined cell culture environment, allowing researchers to tightly and reproducibly control the cell culture environment for predictable cell expansion and differentiation outcomes
  • Pre-coated and ready to use at room temperature, streamlining experimental workflows, which can minimize the risk of experimental failure due to inconsistent ECM self-coating, as well as the risk of pre-coated biological performance failure due to incorrect storage
  • Consistency built on cGMP-compliant manufacturing and animal-free traceability, mitigating variability and risk of contamination from adventitious organisms common to animal-sourced material
  • Simplifies supply chain requirements by removing the need for costly cold chain transport and storage
  • Scalable formats to meet a wide range of cell expansion needs to suit any stage of research
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How to Buy

Purchasing Options

Applications and Use

PureCoat in Action

What’s New

Featured Products, Resources, and More

Try PureCoat at No Cost

Try PureCoat at No Cost

Enhance your defined, animal-free cell environments

Request a PureCoat ECM evaluation and receive a free sample.

Give PureCoat ECM mimetic cultureware—a next-generation family of chemically defined, animal-free surfaces from Corning—a try. Request a complimentary sample. 

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Webinar: PureCoat ECM Mimetic Cultureware

Webinar: PureCoat ECM Mimetic Cultureware

Join Dr. Deepa Saxena, Senior Development Scientist, as she presents this informative webinar.

Defined, Animal-free Synthetic Surfaces for Culture of Cell Types Relevant in Clinical Research.

Growing concerns about introducing human- and animal-derived pathogens into cell culture necessitate the need for animal-free cell culture environments. Learn how PureCoat ECM mimetic cultureware presents a defined, synthetic surface for cell culture without compromising performance.

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Frequently Asked Questions

Frequently Asked Questions

Have questions about PureCoat? Take a look at these answers to frequently asked questions.

PureCoat ECM Mimetic Cultureware: Frequently Asked Questions

From manufacturing details to shelf life and storage requirements, get answers to common questions about PureCoat surface coatings.

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PureCoat Cultureware Brochure

PureCoat Cultureware Brochure

Enable a fully defined cell culture environment with the scientifically defined

PureCoat ECM Mimetic Cultureware: The First Animal-free Synthetic Surface to Mimic Natural ECM

From product details and cell line compatibility to application guidance, learn more about how you can promote optimal cell binding and signaling in a broad range of serum-free, xeno-free, and animal-free media formulations.

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