The photo-reactive Universal-BIND surface is uniquely designed to covalently immobilize biomolecules via abstractable hydrogen using ultraviolet (UV) illumination, resulting in a carbon-carbon bond. All that is required is a UV crosslinker; no surface preparation or pre-activation is necessary.
Although the linkage is non-specific and does not allow for site-directed orientation of a biomolecule, Universal-BIND surface is very useful for the following applications:
- Immobilization of double-stranded DNA
- Immobilization of antigens of unknown structure (available functional groups unidentified)
- Immobilization of samples containing a mixture of biomolecules, such as cell lysate samples
- Immobilization of other non-proteinaceous molecules, such as glycolipids