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Corning Cell Culture Surfaces:
Corning^® CellBIND^® Polystyrene Surface

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The unique Corning CellBIND surface enhances attachment making it easier to grow fastidious cells under difficult conditions, such as reduced-serum or serum-free medium, resulting in higher cell yields. Developed by Corning scientists, this patented (US Patent # 6,617,152) technology uses a microwave process for treating the culture surface. This new process improves cell attachment by incorporating significantly more oxygen into the cell culture surface, rendering it more hydrophilic and increasing surface stability. 

Electron Spectroscopy Chemical Analysis (ESCA) shows that the amount of oxygen incorporated into the Corning CellBIND surface is over 60% higher than with the traditional tissue culture surface treatment (Table 1). Unlike poly-D-lysine and biological coatings, the Corning CellBIND surface is a nonbiological surface that requires no special handling or storage. Because the polymer is treated, rather than coated, the surface is consistent and stable.

Corning CellBIND Surface Benefits:

• Quickly adapts cells to reduced serum or serum-free conditions
• May eliminate the need for expensive coatings
• Improves attachment and yield
• No special handling or storage required

Corning CellBIND Surface works with:

• Primary Cultures – helps them attach without need for expensive biological coatings
• Roller bottle cultures – cells attach faster and remain attached longer
• Transfected cells – helps them stay attached when over-expressing proteins