Corning® Labware with Ultra-Web™ Synthetic Surfaces

Corning Surfaces

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Corning® labware with the innovative Ultra-Web™ Synthetic nanofiber surfaces improve the performance and functionality of cultured cells. These surfaces offer cells a more in vivo-like fibrillar topography that, unlike biological coatings, are more stable, more consistent lot to lot, and animal component-free. They can be modified by linking cell attachment and growth factors to improve the culture environment.

Scanning electron micrograph of Ultra-Web™ surface (Left panel) and atomic force micrograph of a surface coated with Collagen IV (right panel) shown at the same scale of magnification. The relative nanofibrillar topographies of the two surfaces are very similar.

SEM cross-sectional (left) and top down (right) images (10,000X) of the Ultra-Web™ Synthetic Surface. The electrospinning process consistently and closely controls the size and shape of each synthetic fiber.

Ultra-Web™ Synthetic Surface Applications:

Growing cells, such as stem cells, liver, neuronal and primary cultures, and cell-based assays, where current surfaces do not provide the necessary cell culture performance or function
Providing an ideal substrate to which researchers can link cell attachment and growth factors for creating more in vivo-like culture environments.

Compare results with the surfaces you are currently using!

Phase contrast microscope images comparing growth of human endothelial cells on the Ultra-Web™ surface (left) and a standard polystyrene tissue culture treated surface (right). The Ultra-Web™ nanofibers do not interfere with visualization or photography of the cells.

Ultra-Web™ Synthetic Surfaces are available with two surface chemistries:

Untreated electrospun polyamide nanofibers with a slightly hydrophilic surface.
A positively charged hydrophilic polyamine surface for enhanced cell attachment or the ability to covalently attach biomolecules.

Ultra-Web™ Synthetic Surface Features:

Synthetic and well defined nanotopography and surface chemistry
Easy to view cells using phase contrast microscopy
Ready to use and room-temperature stable
Irradiation sterilized (SAL 10^-6)
QC and lot controlled
Compatible with most existing cell culture protocols and cell detachment methods
Can be used with ECM molecules and hydrogel systems

Learn more about the Ultra-Web™ Synthetic Surfaces in our product catalog.

Ultra-Web™ Synthetic Surfaces are available on 100mm dishes and 96 well plates.

100mm Dishes:

96 Well Microplates:

Ultra-Web™ Synthetic surfaces are for in vitro research use only. Not for diagnostic use or therapeutic procedures. Not for in vivo human use.

Technical Literature

Ultra-Web is a U.S. registered trademark of Donaldson Company, Inc. MN, 55431