Corning and Promega Launch Web-based Microarray Tool
Innovative new tool used to verify cDNA labeling efficiency
Acton, Massachusetts, February 2004 -
The downstream costs associated with conducting a microarray experiment can be relatively high, especially if there is a flaw in the cDNA labeling process. Corning Incorporated and Promega Corporation introduce a new online tool that allows printing groups and microarray end-users to verify the quality of the cDNA labeling reaction prior to hybridization.
The tool, similar to a mortgage calculator, was designed by Corning Application Scientists in collaboration with Promega Technical Service Scientists. The calculator is an extension of mathematical formulae found in Corning's Pronto!™ Reagent System Instruction Manual.
Based on input spectrophotometry data, the user-friendly calculator will make recommendations on the amount of labeled cDNA to use for hybridization. This tool also includes troubleshooting tips that cover approximately 95% of the potential problems that could arise during the labeling process. If results are not within an acceptable range, it will offer suggestions as to what to check in the process.
"As with any scientific experiment, the key to microarray experiments is reproducibility," said Michael Briggs Ph.D., applications scientist, Corning Life Sciences. "The calculator gives investigators reassurance that their yield of cDNA and the amount incorporation of incorporated nucleotides are within and acceptable range. The labeling reaction is a good place in the microarray process to spend a little extra time to ensure reliable, reproducible results."
To use the calculator log onto www.prontosystems.com.
For additional information on Corning Life Sciences products or services, please
contact a customer service representative at 1-800-492-1110, toll free in the
United States, (+1) 978-635-2200 internationally, or visit
www.corning.com/lifesciences
.
For additional information on Promega products or services, please contact a
customer service representative at 1-800-356-9526, toll free in the United
States, and 1-608-274-4330 internationally, or visit
www.promega.com
.
About the companies
Established in 1851, Corning Incorporated (www.corning.com
) is a diversified technology company that concentrates its efforts on
high-impact growth opportunities. Corning combines its expertise in specialty
glass, ceramic materials, polymers and the manipulation of the properties of
light, with strong process and manufacturing capabilities to develop, engineer
and commercialize significant innovative products for the telecommunications,
information display, environmental, semiconductor, and life sciences
industries.
Promega Corporation is a global leader in providing innovative solutions for the
life sciences industry. The company's 1,200 products enable scientists
worldwide to advance knowledge in cellular analysis, proteomics, and genomics
research with applications in drug discovery, molecular diagnostics, and human
identification. Founded in 1978, the company is headquartered in Madison,
Wisconsin, USA, and has extensive international distribution. For more
information about Promega, visit www.promega.com.
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