We use cookies to ensure the best experience on our website.
View Cookie Policy
_self
Accept Cookie Policy
Change My Settings
ESSENTIAL COOKIES
Required for the site to function.
PREFERENCE AND ANALYTICS COOKIES
Augment your site experience.
SOCIAL AND MARKETING COOKIES
Lets Corning work with partners to enable social features and marketing messages.
ALWAYS ON
ON
OFF

Explore Organoid Model Environments

Explore Organoid Model Environments

Organoids are generated from both pluripotent stem cells (PSCs) and adult stem cells (ASCs). Self-renewal and differentiation of stem cells is influenced by growth factors and extracellular matrices (ECM) that provide the required scaffold to support cell attachment and growth during organoid formation. Hydrogels such as Corning Matrigel® Matrix and Corning® Collagen are popular scaffold choices to support cell expansion in organoid cultures.

Stem cells and/or organ progenitors from normal or diseased tissue can be mixed with Matrigel matrix or Collagen to create mini-organs of the kidney, thyroid, liver, brain, lung, intestine, prostate, and pancreas. Organoids support advancements in the study of organogenesis, disease modeling, and subsequent patient-specific therapies.  For example, the combination of genome editing using CRISPR-Cas9 and organoid cultures allows researchers to evaluate DNA repair of patient-specific mutations found in certain cancers and perform genetic screens. Hydrogels such as Collagen and Matrigel Matrix can be used as bio-inks to allow precise positioning and embedding of living cells/organoids during 3D bioprinting.  Organoids are also being used as physiologically relevant models for the development of new therapeutic drug candidates.

Publications

Supporting Publications for Organoid Culture

Supporting Publications for Organoid Culture

Cancer Phenotypes

Discover research on organoid cultures for the analysis of cancer phenotypes.

Read More

Engineering Stem Cell Organoids

Learn more about basic approaches to generate stem cell-based organoids, their advantages and limitations, and how bioengineering strategies can be implemented.

Read More

Disease Modeling

Discover research examining disease modeling in stem-cell derived 3D organoid systems.

Read More

Organoids and Epithelial Translational Medicine

Learn more about the advantages of stem cell-derived organoid models over existing culture systems, as well as recent advances in epithelial tissue-specific organoids.

Read More

Testimonials

Customer Success Stories

Customer Success Stories

"Matrigel Matrix seems to have a lot of excellent growth factors in there." - Colin Bishop, Ph.D., Professor, Wake Forest Baptist Health

Read more about how Corning Matrigel matrix is helping to make 3D cell culture easier than ever at Wake Forest Baptist Health. 

Learn More

"We can recapitulate the same biological behavior and histopathological features..." - Amanda Linkous Ph.D.

Learn more about how Amanda Linkous, Ph.D. cultured and differentiated cerebral organoids in Corning Matrigel Matrix to mimic biological behavior and histopathological features of patient glioblastomas. 

Learn More

Solutions

Solutions for Organoid Models

Applications

Organoid Model Applications

Organoid Model Applications

  

Support

Scientific Support–Setting a New Industry Standard

Compartir